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N/A N=1,201 Randomized Single-blind Screening

5-Cog Battery for Detecting Cognitive Impairment and Dementia

Dementia · Cognitive Impairment · Mild Cognitive Impairment · Neurocognitive Disorders

Enrolled (actual)
1,201
Serious AEs
0.0%
Results posted
Jan 2024
Primary outcome: Primary: New Occurrence in Dementia Care-A Composite Endpoint Including New Cognitive Diagnoses, Laboratory Investigations Related to Cognitive Impairment, New Dementia Prescriptions, and Cognitive Related Referrals. — 111; 41 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
5-Cog (Other); Health Literacy & Grip Assessment (Other)
Age
Older Adult · 65+ yrs
Sex
All
Sponsor
Albert Einstein College of Medicine
Primary completion
Dec 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
New Occurrence in Dementia Care-A Composite Endpoint Including New Cognitive Diagnoses, Laboratory Investigations Related to Cognitive Impairment, New Dementia Prescriptions, and Cognitive Related Referrals.
111; 41
SECONDARY
New Occurrence of in Health Care Utilization
106; 96

Summary

Despite the availability of numerous cognitive assessment tools, cognitive impairment related to dementia is frequently under-diagnosed in primary care settings. The investigators have developed a 5-minute cognitive screen (5-Cog) coupled with a decision tree to overcome the technical, cultural and logistic barriers of current cognitive screens to improve dementia care in primary care patients with cognitive concerns.

Eligibility Criteria

Inclusion Criteria

  • Age 65 and older.
  • Presence of cognitive or memory concerns expressed by patient, caregiver, health care provider or other source who knows the patient.
  • Registered as patient at Montefiore Medical Center and have a primary care doctor appointment that day.
  • Able to hear and see well enough to complete intervention or control assessments.
  • English or Spanish speaking.

Exclusion Criteria

  • Prior diagnosis of dementia or MCI as ascertained by ICD-10 codes or the documentation of prescription for anti-dementia medications in EMR. Patients with a diagnosis containing any of the following terms will be excluded:
  • "Dementia"
  • "Mild Cognitive Impairment"
  • "Alzheimer's Disease"
  • "Creutzfeldt-Jakob Disease"
  • "Major Neurocognitive Disorder"
  • "Minor Neurocognitive Disorder"

Patients with any of the following medications documented in their EMR will be excluded (generic = brand):

  • Donepezil = Aricept
  • Memantine = Namenda
  • Rivastigmine = Exelon
  • Galantamine = Razadyne
  • Donepezil and Memantine = Namzaric
  • Adults who are permanent residents of a nursing facility.
  • Patients who do not speak English or Spanish.
  • Patients who are not seeing a primary care physician at the clinic that day.
  • Patients who are blind or deaf or cannot hear loud voice even with hearing aids.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03816644). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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