N/A
N=31
HIV+ Substance Users Released From Jail
HIV/AIDS · Substance Use Disorders
Bottom Line
View on ClinicalTrials.gov: NCT03834779 ↗Enrolled (actual)
31
Serious AEs
58.1%
Results posted
Feb 2023
Primary outcome: Primary: Number of Participants With Undetectable HIV Viral Load — 2; 3 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- DOORS-CHW Intervention (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Texas Southwestern Medical Center
- Primary completion
- Apr 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Undetectable HIV Viral Load |
2; 3 | — |
| SECONDARY Number of Participants Who Are Positive/Negative for Substance Use as Assessed Via Urine Drug Screen |
4; 8; 5; 1 | — |
Summary
The long-term goal of this project is to improve HIV and substance use outcomes and reduce recidivism for HIV+ substance users released from jail. The overall objective of the proposed R34 project is to develop and pilot test a multi-sector community-clinic collaborative intervention that can subsequently be implemented on a larger scale (as part of a future R01) to achieve this goal. Our central hypothesis is that HIV+ substance users released from jail can successfully overcome obstacles to re-entry and continuity of HIV care with individualized, culturally competent assistance in navigating both social and medical services.
Aim 1: Develop and refine a collaborative CHW and re-entry program intervention that targets HIV outcomes, substance use and recidivism in HIV+ jail releasees.
Aim 2: Conduct a pilot randomized controlled trial comparing the collaborative intervention (n=40) compared to treatment as usual (n=40) in HIV+ substance users released from jail.
Eligibility Criteria
Inclusion Criteria
- HIV-infected AND
- ≥18 years old AND
- report or have medical records documenting any opioid (illicit or prescription misuse), stimulant (cocaine, ecstasy, or amphetamines), or heavy alcohol use (as determined by the 3-item Alcohol Use Disorders Identification Test (AUDIT-C) within the past 12 months
- Provide two forms of contact information (address, phone number, email, other locator info) AND
- HIV VL >200 copies/mL within past 90 days OR
- No HIV visit in 6 months OR Self-reported non-adherence to medications
Exclusion Criteria
- Unwilling to participate
- Unable to consent
- Does not speak English
- Unwilling to participate
- Unable to consent
- Does not plan to remain in greater Dallas area after release Sentenced to prison or other court-mandated program for ≥6 months
- Does not speak English
- Have an acute medical or psychiatric disorder that would, in the judgment of the PI, make participation difficult or unsafe.
Data sourced from ClinicalTrials.gov (NCT03834779). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.