Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
N/A N=6 Randomized Quadruple-blind Treatment

Cognitive Rehab for Parkinson's

Parkinson's Disease · Mild Cognitive Impairment

Bottom Line

View on ClinicalTrials.gov: NCT03836963 ↗
Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Jul 2024
Primary outcome: Primary: Change in NIH Sponsored Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) Executive Composite Score — 0.34; -.42 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
cognitive training (Behavioral); active control cognitive training (Behavioral); memory strategy training (Behavioral)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
VA Office of Research and Development
Primary completion
Oct 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in NIH Sponsored Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) Executive Composite Score		 0.34; -.42 —

Summary

This study will examine the feasibility of an at-home cognitive training program that incorporates both memory training and online computerized cognitive training (CCT) software. Data will also be collected to determine if this program improves thinking and memory as well as everyday function. The hypothesis is that memory and cognitive training combined , compared to memory training alone or will lead to greater improvements in cognitive performance and daily function.

Eligibility Criteria

Inclusion Criteria

  • Veterans who seek services at Hines VA Hospital
  • Diagnosis of PD as determined by the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria
  • Meet criteria for having mild cognitive impairment
  • Receiving stable (i.e., no changes in medication and medication dose) medication and who are expected to remain on stable medication for the duration of the RCT
  • 50 years or older
  • Speak and read English

Exclusion Criteria

  • Dementia
  • Failure to demonstrate decision making capacity
  • Cholinesterase inhibitor medication
  • History of deep brain stimulation surgery
  • Severe depression
  • Severe anxiety
  • Severe apathy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03836963). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search