N/A
Completed N=164
Goal2Quit + NRT Sampling
Cigarette Smoking · Smoking Cessation · Depression
Source: ClinicalTrials.gov NCT03837379 ↗
Enrolled (actual)
164
Serious AEs
0.0%
Results posted
May 2023
Primary outcomePrimary: 7 Day Point Prevalence Abstinence — 1; 16 Participants
Summary
The goal of this work is to develop, systematically evaluate, and clinically test an integrated cessation intervention comprised of a depression-specific Behavioral Activation (BA) for cessation mobile app ("Goal2Quit") packaged with nicotine replacement therapy (NRT) sampling. This integrated intervention will address the need for an easily disseminable, evidence-based, depression-specific cessation intervention for delivery via primary care.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 7 Day Point Prevalence Abstinence |
1; 16 | — |
| SECONDARY Mean Score of Depressive Symptoms |
-6.97; -9.06 | — |
Eligibility Criteria
Inclusion Criteria
- Current elevated depressive symptoms defined as a score of > 10 (at least mild depression) on the Patient Health Questionnaire-8 (PHQ-8)
- Current smoking, defined as smoking 10+ cigarettes/day, for 25+ days out of the last 30, for the last 6+ months
- Ownership of an Android or iOS smartphone
- Age 18+
- Possess a valid e-mail address that is checked daily to access follow-up assessments
- English fluency
Exclusion Criteria
- Contraindications for NRT (pregnancy/intention to become pregnant/breastfeeding, recent cardiovascular trauma/uncontrolled hypertension) - Severe visual impairment, which may limit ability to utilize an app
Data sourced from ClinicalTrials.gov (NCT03837379). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.