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N/A N=50 Randomized Double-blind Treatment

Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence

Pelvic Organ Prolapse · Urinary Incontinence,Stress · Urinary Incontinence, Urge · Bowel Dysfunction · Sexual Dysfunction

Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Number of Participants With Stress Urinary Incontinence — 10; 13 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Laparoscopic Burch Colposuspension (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Northwestern University
Primary completion
Sep 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Stress Urinary Incontinence
10; 13
SECONDARY
Number of Participants With Urinary Urgency Incontinence
1; 2
SECONDARY
Number of Participate With Urinary Frequency
2; 4
SECONDARY
Number of Participants With Urinary Retention
1; 3
SECONDARY
Number of Participants With Urinary Tract Infection
2; 1
SECONDARY
Pelvic Organ Prolapse Symptoms
8.3; 2.1
SECONDARY
Bowel Symptoms
6.3; 6.7
SECONDARY
Sexual Function
10.5; 12.0
SECONDARY
Number of Participants With Surgical Complication
3; 5

Summary

This study evaluates the addition of a laparoscopic Burch colposuspension procedure at the time of laparoscopic sacrocolpopexy to prevent stress urinary incontinence. Half of the participants will undergo Burch colposuspension procedure at the time of sacrocolpopexy, and half of the participants will undergo sacrocolpopexy alone.

Eligibility Criteria

Inclusion Criteria

  • English or Spanish speaking and reading
  • Symptomatic pelvic organ prolapse with any compartment at or beyond the hymen
  • Stress-continent, as defined as response of "no" to question 17 of PFDI-20: "Do you usually experience urine leakage related to coughing, sneezing, or laughing?", as well as a negative empty supine stress test.
  • Planning laparoscopic or robotic sacrocolpopexy, with or without hysterectomy
  • Have completed childbearing

Exclusion Criteria

  • Adults unable to consent
  • Pregnant women or patients desiring future pregnancy
  • Patients undergoing uterine sparing surgery
  • Individuals under age 18
  • Prior procedure for stress urinary incontinence
  • Prior retropubic surgery
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03841513). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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