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Home › Conditions › pelvic organ prolapse

Pelvic organ prolapse

Subtypes of Pelvic organ prolapse

Uterine prolapse 1 Vaginal prolapse 1

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for pelvic organ prolapse

45 trials tracked for pelvic organ prolapse: 13 in phase 3 or 4 and 8 with published results. The most-cited published study has 45 citations.

45Trials tracked
13Phase 3 & 4
0Recruiting
8With published results
Phase distribution
Phase 4 11 Phase 3 2 Phase 2 4 Other / NA 28
  1. Phase 4 Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery Completed · 45 cited
  2. Phase 4 Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse Completed · 32 cited
  3. Phase 3 Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery Completed · 29 cited
  4. Phase 4 Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen Completed · 21 cited
  5. Phase 4 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair Completed · 19 cited
  6. Phase 4 Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery Completed · 18 cited
Show 39 more trials
  1. Phase 3 Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Completed · 9 cited
  2. Phase 4 Gabapentin for Postop Pain After SSLF Completed · 4 cited
  3. Phase 4 Efficacy Study of Vaginal Mesh for Anterior Prolapse Completed
  4. Phase 4 Lessons on Urethral Lidocaine in Urodynamics Completed
  5. Phase 4 Intraperitoneal Bupivacaine for Pelvic Organ Prolapse Completed
  6. Phase 4 Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery Completed
  7. Phase 4 Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor Completed
  8. Phase 2 Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery Completed
  9. Phase 2 Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial Completed
  10. Phase 2 Gentamicin Intravesical Efficacy for Infection of Urinary Tract Completed
  11. Phase 2 Urinary Track Infection Prevention After Urogynecological Surgery Completed
  12. N/A Pelvic Floor Repair Systems for Prolapse Repair Completed
  13. N/A A Long Term Follow up of Anterior Meshes for Recurrent Prolapse Completed
  14. N/A Calistar A vs. Calistar S - Comparative Cohort Retrospective Analysis of Single Incision POP Systems Completed
  15. N/A Same Day Discharge After Minimally-invasive Sacrocolpopexy Completed
  16. N/A Permanent Versus Absorbable Colpopexy Trial Completed
  17. N/A Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis Completed
  18. N/A Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy Completed
  19. N/A Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study Completed
  20. N/A The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study Completed
  21. N/A Efficacy Study of Vaginal Mesh for Prolapse Completed
  22. N/A Apical Support During Hysterectomy for Pelvic Organ Prolapse Completed
  23. N/A Xenform Postmarket Surveillance Study Completed
  24. N/A Performance of Tension Free Vaginal Mesh (Prolift) Versus Conventional Vaginal Prolapse Surgery in Recurrent Prolapse. Completed
  25. N/A Feasibility Study of the Reia Vaginal Pessary Completed
  26. N/A Smartmesh Technology in Pelvic Floor Repair Procedures Completed
  27. N/A Uphold LITE Post-Market Surveillance Study Completed
  28. N/A Early Feasibility Study of the Reia Vaginal Pessary Completed
  29. N/A Educating Women About Pelvic Floor Disorders During Pregnancy Completed
  30. N/A Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery Completed
  31. N/A A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension Completed
  32. N/A Postoperative Virtual Clinical Encounters Completed
  33. N/A Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use Completed
  34. N/A Uterosacral Ligament Suspension Clip Completed
  35. N/A Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence Completed
  36. N/A Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies Completed
  37. N/A Pudendal Nerve Block in Vaginal Surgery Completed
  38. N/A Sacro-Spinous Ligaments Anterior Apical Anchoring Completed
  39. N/A Impact of Decision Aids in Urogynecology Completed

Showing the 45 most-cited and recently-updated of 45 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review of 41 RCTs evaluates surgical options for anterior compartment prolapse
ENT (Otolaryngology) Sys. Review
Systematic review of 41 RCTs evaluates surgical options for anterior compartment prolapse Researchers find prolapse surgery risks vary by method used
This systematic review synthesizes data from 41 randomized controlled trials involving 4531 women with anterior compartment prolapse.
Women choosing prolapse surgery face different risks depending on the method used, with long-term safety for mesh still unknown.
Cochrane Apr 25, 2026
Systematic review finds 54.8% of Indian women with reproductive morbidities seek treatment
OB/GYN & Women's Health Meta-analysis
Systematic review finds 54.8% of Indian women with reproductive morbidities seek treatment Half of Indian women ignore reproductive pain
This systematic review and meta-analysis examined health-seeking behavior for reproductive morbidities among Indian women.
Ignoring common reproductive problems like pelvic pain or irregular periods leads to worse health outcomes for millions of women in India.
Frontiers Apr 11, 2026