N/A N=272 Smartmesh Technology in Pelvic Floor Repair Procedures
Pelvic Organ Prolapse
Primary: Number of Patients With a Composite Outcome : Bladder Wound, Rectum Wound, Abnormal Bleeding — 6 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=698 Pelvic Floor Repair Systems for Prolapse Repair
Pelvic Organ Prolapse
Primary: Percent of Subjects With an ICS (International Incontinence Society) POP-Q (Pelvic Organ Prolapse Quantification System) Stage of </= Stage I in the Posterior…
N/A N=190 Performance of Tension Free Vaginal Mesh (Prolift) Versus Conventional Vaginal Prolapse Surgery in Recurrent Prolapse.
Pelvic Organ Prolapse
Primary: Prolapse by "Pelvic Organ Prolapse Quantification System" (POP-Q), at 12 Months — 8; 38; 75; 46 participants — p=<0.05
Phase 2 N=337 Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial
Pelvic Organ Prolapse
Primary: Number of Participants With Treatment Failure Defined as Subsequent Treatment for Urinary Incontinence, Signs or Symptoms of Bothersome Urinary Incontinence — 39; 85…
N/A N=374 Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial
Pelvic Organ Prolapse (POP)
Primary: Surgical Success — 25; 30; 28; 27 Participants
Phase 4 N=91 Intraperitoneal Bupivacaine for Pelvic Organ Prolapse
Pelvic Organ Prolapse
Primary: Pain Score at 4 Hours — 3.16; 3.77 score on a scale
N/A N=15 Early Feasibility Study of the Reia Vaginal Pessary
Pelvic Organ Prolapse · Prolapse
Primary: The Ability of the Study Device to be Retained During Valsalva Compared to the Ability of the Subject's Current Pessary to be Retained During Valsalva (Change in…
N/A N=30 Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
Pelvic Organ Prolapse (POP)
Primary: Palpability of the Restorelle Direct Fix Anterior and Posterior (A&P) — 30; 0; 0; 0 participants
N/A N=58 Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use
Vaginal Vault Prolapse · Pelvic Organ Prolapse · Uterine Prolapse
Primary: Patient Global Impression of Improvement (PGI-I) Score — 39 Participants
N/A N=49 Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy
Pelvic Organ Prolapse
Primary: Number of Participants With Recurrence of Pelvic Organ Prolapse — 0; 0 Participants
N/A N=78 Feasibility Study of the Reia Vaginal Pessary
Pelvic Organ Prolapse
Primary: Pelvic Floor Distress Inventory-20 (PFDI-20) — 49.46; 62.75 score on a scale — p=.0021
Phase 2 N=29 Evaluation of Outcomes of Restoring Pelvic Floor Support With TOPAS in Women With Moderate Fecal Incontinence Symptoms
Fecal Incontinence
Primary: Fecal Incontinence Incidence From Baseline (Pre-treatment) Through 24 Months Post-treatment — 6.9; 3.0; 3.7; 3.7 Number of FI episodes/14 day period
N/A N=236 Apical Support During Hysterectomy for Pelvic Organ Prolapse
Pelvic Organ Prolapse
Primary: Proportion of Patients Having Concurrent Apical Suspension Performed — 66 Participants
Phase 4 N=199 Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen
Pelvic Organ Prolapse · Urogenital Prolapse · Vaginal Vault Prolapse
Primary: Surgical "Failure" Defined by (i) Anatomic Assessment of Prolapse, (ii) Presence of Bulge Symptoms, and/or (Iii) Retreatment of Prolapse — 18; 8 Participants
N/A N=183 Study of Uterine Prolapse Procedures - Randomized Trial
Uterovaginal Prolapse
Primary: Cumulative Failure — 78; 69; 9; 16 Participants
Phase 4 N=30 Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor
Pelvic Organ Prolapse · Menopause
Primary: Vaginal Wall Composition: Epithelium (Intention to Treat) — 413.9; 314.1 microns — p=0.21
Phase 3 N=152 Effect of Phenazopyridine on Prolapse Surgery Voiding Trials
Urinary Retention Postoperative
Primary: Number of Participants With Postoperative Urinary Retention After Pelvic Organ Prolapse Surgery (INTENT-TO-TREAT) — 30; 25 Participants
N/A N=204 Permanent Versus Absorbable Colpopexy Trial
Pelvic Organ Prolapse
Primary: Number of Participants With Vaginal Mesh or Suture Exposure — 5; 8 Participants — p=0.30
N/A N=48 A Long Term Follow up of Anterior Meshes for Recurrent Prolapse
Genital Diseases, Female · Pelvic Organ Prolapse
Primary: The Number of Participants With a Current Mesh Erosion or Treated for a Mesh Erosion Since Inserted — 5 Participants
N/A N=74 Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study
Pelvic Organ Prolapse
Primary: Percentage of Participants With POP-Q Stage Improvement Assessed by POP-Q Stage Improvement Based Upon Grading of Prolapse of the Anterior, Posterior, or Combined…
Phase 4 N=204 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
Pelvic Organ Prolapse
Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05
Phase 4 N=132 Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Urinary Bladder, Overactive
Primary: Change in OAB Symptoms Post Pubovaginal Sling Operation — 63; 21; 4 participants — p=0.001
N/A N=120 Educating Women About Pelvic Floor Disorders During Pregnancy
Pelvic Floor Disorders · Stress Urinary Incontinence · Pelvic Organ Prolapse
Primary: Prolapse and Incontinence Knowledge Questionnaire (PIKQ) — 17; 17; 21; 21 score on a scale
N/A N=374 The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study
Pelvic Organ Prolapse
Primary: Surgical Failure — 17; 22; 20; 14 Participants
N/A N=710 Uphold LITE Post-Market Surveillance Study
Pelvic Organ Prolapse
Primary: Primary Efficacy Endpoint - Number of Participants With Composite Anatomic and Symptomatic Success at 36 Months — 201; 389; 199; 384 Participants — p=0.056
N/A N=132 Postoperative Environment on Pain Following Pelvic Reconstructive Surgery
Postoperative Pain
Primary: Visual Analog Scale (VAS) Score for Pain — 28.0; 24.5 millimeter (mm) — p=0.57
N/A N=300 The Effect of Pregnancy and Labour on the Pelvic Floor Diagnosed With 3D and 4D Ultrasound
Obstetric; Injury Pelvic Floor
Primary: Change in Levator Hiatus Area at Rest Measured Via 3-dimensional Ultrasound at Gestational Week 21 and 37. — 2.0 cm
N/A N=99 Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
Anterior Vaginal Wall Prolapse · Cystocele · Pelvic Organ Prolapse
Primary: Prospective Randomized Trial of Anterior Colporrhaphy Vs. Cystocele Repair Using Polypropylene Mesh or Porcine Dermis — 5; 14; 12 Participants
N/A N=44 A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension
Pelvic Organ Prolapse · Cystocele · Uterine Prolapse
Primary: Pelvic Organ Prolapse Quantification Exam (POP-Q) Point C — -7.25; -7 cm
N/A N=255 Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence
Stress Urinary Incontinence · Pelvic Floor Disorders
Primary: Number of Participants With Subjectively Bothersome Stress Incontinence — 129; 126 Participants