N/A N=93 Randomized Double-blind Prevention

Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns

Smoking · Tobacco Use

Bottom Line

View on ClinicalTrials.gov: NCT03844672 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2024

Primary outcome: Primary: Mean Cigarettes Per Day — 13.1; 12.6; 12.2; 13.3 cigarettes per day

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Low Power (Behavioral); High Power (Behavioral); Low Concentration (Behavioral); High Concentration (Behavioral)
Age: Adult, Older Adult · 21+ yrs
Sex: All
Sponsor: Medical University of South Carolina
Primary completion: Oct 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Mean Cigarettes Per Day	13.1; 12.6; 12.2; 13.3	—
SECONDARY Average Number of E-cigarette Puffing Episodes	4.8; 6.5; 5.4; 3.0	—
SECONDARY Number of Choices to Smoke Cigarette in Lab Setting	1.7; 2.4; 1.8; 2.4	—

Summary

The purpose of this project is to understand how different e-cigarettes influence their likeability and use among current smokers who try using e-cigarettes. Participants will receive an e-cigarette to sample over a three week period. During this time period they will complete daily electronic diaries and weekly lab visits. The results from this information will help understand how different types of e-cigarettes are likely to influence cigarette and e-cigarette use.

Eligibility Criteria

Inclusion criteria include

adults who have been smoking daily
interested in using e-cigarettes
who have a smartphone that can receive text messages and access to the internet or has an e-mail account that they check daily

Exclusion criteria include

minimal prior e-cigarette use
use of tobacco products other than cigarettes
current use of cessation medications
pregnant, trying to become pregnant, or breastfeeding,
recent history of cardiovascular distress in the last three months (e.g., arrhythmia, heart attack, stroke, uncontrolled hypertension),
household member currently enrolled in the study.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03844672). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.