N/A N=222 Randomized Supportive Care

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions

Sickle Cell Disease · Chronic Kidney Diseases · Systemic Lupus Erythematosus · Childhood Cancer · Inflammatory Bowel Diseases

Bottom Line

View on ClinicalTrials.gov: NCT03938324 ↗

Enrolled (actual)

222

Serious AEs

0.0%

Results posted

Jul 2025

Primary outcome: Primary: Change in Self-management as Measured by the Partners in Health Scale — 6.7; 6.5; 6.8; 6.6 score on a scale — p=0.0034

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: PiCASO Intervention Group (Behavioral); Sham Comparator: Attention Control Group (Behavioral)
Age: Pediatric, Adult · 16+ yrs
Sex: All
Sponsor: Duke University
Primary completion: Jun 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Self-management as Measured by the Partners in Health Scale	6.7; 6.5; 6.8; 6.6; 6.9; 6.6	0.0034 sig
PRIMARY Patient Activation as Measured by the Patient Activation Measure (PAM-13)	70.0; 68.8; 72.4; 70.8; 74.9; 72.8	0.5137
SECONDARY Change in Transition Readiness as Measured by the Transition Readiness Questionnaire (TRAQ 20)	4.1; 3.9; 4.2; 4.0; 4.3; 4.1	0.4107
SECONDARY Change in Health-related Quality of Life as Measured by the Short Form Health Survey (SF12) - Mental Component Summary (MCS)	45.5; 45.1; 46.1; 45.1; 46.7; 45.1	0.1708
SECONDARY Change in Emotional Health as Measured by the Brief Symptom Inventory (BSI 18)	9.7; 10.7; 9.5; 10.5; 9.3; 10.4	0.7982

Summary

The purpose of this study is to test the efficacy of a peer support coaching intervention to improve activated chronic illness self-management versus an attention control group in 225 adolescents and young adults with childhood onset chronic conditions.

Eligibility Criteria

Inclusion Criteria

AYA 16 to 22 years
Childhood onset chronic condition from 1 of 3 condition categories
Read and speaks English
Access to internet via computer or Smart Phone
Access to telephone (Smart Phone not required as text feature can be accessed via internet)

Exclusion Criteria

Diagnosed cognitive dysfunction
Need for English translator

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Data sourced from ClinicalTrials.gov (NCT03938324). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.