Telitacicept plus standard therapy in SLE patients with antiphospholipid antibodies
New Lupus Drug May Help Patients With Specific Antibodies
This prospective observational cohort study evaluated telitacicept added to standard therapy in 20 SLE patients with antiphospholipid antibo…
A new treatment shows promise for a tough lupus group by targeting specific immune cells.
Narrative review explores TLR7 and TLR9 signaling networks within systemic lupus erythematosus and Sjögren's disease contexts.
Why Lupus and Sjögren’s Flares May Start in Your Cells’ “Mailroom”
This narrative review examines the role of TLR7 and TLR9 signaling networks in systemic lupus erythematosus and Sjögren's disease. The autho…
Understanding how these immune sensors misfire could lead to more precise treatments that calm flares without shutting down your whole immun…
Narrative review discusses screening and prevention in rheumatic and musculoskeletal disease populations.
Joint Pain May Signal Hidden Risk in Your Legs
This narrative review examines patients with rheumatic and musculoskeletal diseases (RMDs), including rheumatoid arthritis and systemic lupu…
Inflammation from autoimmune conditions can silently damage blood vessels in your legs.
Narrative mini-review discusses mechanisms driving coronary atherosclerosis in patients with systemic lupus erythematosus
Why Lupus Can Speed Up Heart Disease, Even in Young People
This narrative mini-review synthesizes mechanistic insights regarding the link between systemic lupus erythematosus and coronary atheroscler…
Understanding how lupus harms blood vessels could help prevent heart attacks in people who don’t look high-risk.
Systematic review of immunosuppression for SLE-associated intestinal pseudo-obstruction
SLE Can Shut Down the Gut — But It Might Be Reversible
This review synthesized 43 cases of SLE-associated intestinal pseudo-obstruction. Corticosteroids were used in all patients, with variable u…
Lupus can paralyze the gut without a blockage, but early treatment with immunosuppressives often reverses this dangerous complication.
Obesity associated with reduced SLE relapse rates in Japanese registry cohort
A Surprising Link Between Weight and Lupus Flares
This observational cohort study of 1134 patients with systemic lupus erythematosus in Japan found that obesity (BMI ≥25 kg/m2) was associate…
Being overweight or mildly obese might lower the risk of lupus relapses, challenging common beliefs about weight and autoimmune disease.
Narrative review explores emerging therapeutic strategies targeting Th17 and Treg balance in systemic lupus erythematosus
Could new drugs restore balance for lupus patients, or is the science still too early?
This narrative review examines emerging therapeutic strategies aimed at restoring the Th17 and Treg balance in patients with systemic lupus …
Doctors are exploring new drugs to restore balance between immune cells in lupus, aiming to stop attacks without shutting down the entire sy…
Case-Control Study Finds No Association Between G6PD Deficiency and Systemic Lupus Erythematosus Risk in Females
G6PD Deficiency Does Not Raise Lupus Risk
This case-control study compared G6PD deficiency rates in 516 female systemic lupus erythematosus patients versus 491 age-matched healthy fe…
Having G6PD deficiency does not make you more likely to develop systemic lupus erythematosus.
Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients.
Lupus Patients Face Hidden Bone Loss Risk
This systematic review and meta-analysis evaluated 59 studies involving patients with systemic lupus erythematosus (SLE) to assess bone heal…
Bone loss affects 1 in 6 lupus patients, a hidden risk often overlooked due to the disease and its treatments.
Case report details KFD patient developing SLE treated with immunosuppression
Your stomach hurts. You throw up. You think it is just food poisoning. But what if your immune system is fighting a hidden battle inside your lymph nodes? This story is about a rare condition that tricks doctors and changes a patient's life forever.
This case report describes a single patient with Kikuchi-Fujimoto disease who subsequently developed systemic lupus erythematosus. The autho…
Severe stomach pain and vomiting from a rare immune disorder can hide a hidden battle in your lymph nodes that tricks doctors into missing t…
Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
Web of White Blood Cells Linked to Pregnancy Risks
A systematic review of emerging evidence indicates that dysregulation of neutrophil extracellular trap (NET) formation and clearance is stro…
A sticky web of white blood cells meant to fight germs can instead trigger serious pregnancy risks like preeclampsia and preterm birth when …
Anifrolumab shows higher remission rates versus placebo in SLE patients regardless of immunosuppressant history
A New Lupus Drug May Work Better If You Start It Sooner
A post hoc analysis of pooled Phase 3 RCT data in 726 patients with moderate-to-severe SLE found higher DORIS remission rates with anifrolum…
Starting a new lupus drug before trying older medications may help patients reach remission faster and with fewer side effects.