N/A
Completed N=15
Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults
Source: ClinicalTrials.gov NCT04026126 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Oct 2022
Primary outcomePrimary: Change in Blood Pressure — -2.94; 0.85 mmHg
Summary
The purpose of this study is to determine if enhanced endothelial arterial distensibility observed with heat therapy translates into improved cardiorespiratory fitness. The following aims are proposed: Aim 1: to determine if chronic heat therapy results in improvements in cardiovascular function. Aim 2: To examine potential mechanism(s) of action of heat therapy in cardiovascular function.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Blood Pressure |
-2.94; 0.85 | — |
| PRIMARY Change in Stroke Volume |
9.02 | — |
| PRIMARY Change in Stroke Volume Variation |
— | — |
| PRIMARY Change in Cardiac Index |
-0.36 | — |
| PRIMARY Change in Systemic Vascular Resistance |
9.02 | — |
| PRIMARY Change in Maximum Oxygen Consumption (VO2max) |
-0.13 | — |
| PRIMARY Change in Concentration of Heat Shock Proteins |
— | — |
| PRIMARY Change in Concentration of Nitric Oxide |
— | — |
| PRIMARY Change in Concentration of Pro/Anti-inflammatory Markers |
— | — |
Eligibility Criteria
Exclusion Criteria
- Current major cardiovascular disease (i.e.: recent myocardial infarction (heart attack), stroke, angina pectoris, high grade coronary vasculopathy or atherosclerosis, severe valvular disease, cardiac dysrhythmia that requires treatment.
- Current treatment with steroids or immunosuppressive agents
- Cancer
- Serious liver disease
- End-stage renal disease
- Judgement by medical provider that heat therapy poses an undue burden or risk
- Women who are pregnant or plan to become pregnant
Data sourced from ClinicalTrials.gov (NCT04026126). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.