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Home › Conditions › Endothelial Dysfunction

Endothelial Dysfunction

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Endothelial Dysfunction

40 trials tracked for Endothelial Dysfunction: 4 in phase 3 or 4 and 1 with published results. The most-cited published study has 11 citations.

40Trials tracked
4Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 3 Phase 3 1 Phase 2 14 Phase 1 5 Other / NA 17
  1. Phase 3 Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans Completed · 11 cited
  2. Phase 4 Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects Completed
  3. Phase 4 The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation Completed
  4. Phase 4 Cardiovascular Effects of Chronic Sildenafil in Men With Type 2 Diabetes Completed
  5. Phase 2 A Phase 1/ Phase 2 Study of TTHX1114(NM141) Completed
  6. Phase 2 A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction Completed
Show 34 more trials
  1. Phase 2 CD36 in Nutrient Delivery and Its Dysfunction Completed
  2. Phase 2 Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial Completed
  3. Phase 2 Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults Completed
  4. Phase 2 A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease Completed
  5. Phase 2 Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome Completed
  6. Phase 2 Rilonacept to Improve Artery Function in Patients With Atherosclerosis Completed
  7. Phase 2 Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function Completed
  8. Phase 2 Targeting Inflammation to Treat Cardiovascular Aging Completed
  9. Phase 2 Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women Completed
  10. Phase 2 Darusentan Effect on PET Uptake Heterogeneity Completed
  11. Phase 2 N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults Completed
  12. Phase 2 Trial of Oral Glutamine on Mitochondrial Function in CKD Completed
  13. Phase 1 Leptin Infusion and Endothelial Vasomotor Response Completed
  14. Phase 1 Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study Completed
  15. Phase 1 Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents Completed
  16. Phase 1 A Trial to Evaluate the Effect of C21 on Endothelial Dysfunction in Subjects With Type 2 Diabetes Completed
  17. Phase 1 Acute Effects of E-Cigarette Aerosol Inhalation Completed
  18. N/A Endothelial Function After Cardiac Surgery Completed
  19. N/A The Cardiovascular Effects of Electronic Hookah Vaping Completed
  20. N/A Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease Completed
  21. N/A Study of Protective Effects of Paricalcitol on Inner Layer of Vessels and Its Protective Effect on Inflammation Completed
  22. N/A FFA-Induced Hypertension and Endothelial Dysfunction Completed
  23. N/A Resveratrol and Vascular Function in CKD Completed
  24. N/A Evaluation of Lipid Emulsion on GCX in Critically Ill Patients Completed
  25. N/A Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women Completed
  26. N/A Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome Completed
  27. N/A Vitamin D Repletion in Coronary Artery Disease Completed
  28. N/A Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function Completed
  29. N/A Passive Mobilization and Vascular Function Completed
  30. N/A Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults Completed
  31. N/A Study of Niacin on Endothelial Function in HIV-infected Subjects With Low High Density Lipoprotein Cholesterol Levels Completed
  32. N/A The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women Completed
  33. N/A Effects of Body Mass Index on the Hyperemic Response to Regadenoson Completed
  34. N/A The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function Completed

Showing the 40 most-cited and recently-updated of 40 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Endothelial dysfunction prevalent in PCI patients; 33.7% developed contrast-associated AKI
Nephrology Cohort
Endothelial dysfunction prevalent in PCI patients; 33.7% developed contrast-associated AKI Study finds kidney injury link to blood vessel health after heart procedures
A prospective observational cohort of 187 PCI patients found 60 cases (33.7%) of contrast-associated AKI.
Poor blood vessel health is linked to kidney injury after heart procedures, a connection found in patients receiving contrast dye for corona…
Frontiers Apr 2, 2026
Resistance exercise after high-carb meal improves postprandial glucose and endothelial function in healthy adults
Physical Medicine & Rehab RCT
Resistance exercise after high-carb meal improves postprandial glucose and endothelial function in healthy adults When should you exercise after a meal to help your blood vessels?
A randomized crossover study in healthy adults found whole-body resistance exercise performed immediately after a high-carbohydrate meal imp…
Doing a full-body workout right after eating helps healthy adults lower blood sugar and improve blood vessel function better than resting or…
Apr 2, 2026