N/A
N=46
Morning Light Treatment for Traumatic Stress: The Role of Amygdala Reactivity
Stress
Bottom Line
View on ClinicalTrials.gov: NCT04117347 ↗Enrolled (actual)
46
Serious AEs
0.0%
Results posted
Mar 2024
Primary outcome: Primary: Change in Amygdala Reactivity as Measured by Blood-oxygen-level-dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Signal — 0.1287; 0.1532; 0.2134; 0.1048 beta weights
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Light therapy A via the Re-Timer® (Device); Light therapy B via the Re-Timer® (Device); Light therapy C via the Re-Timer® (Device)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Michigan
- Primary completion
- Mar 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Amygdala Reactivity as Measured by Blood-oxygen-level-dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Signal |
0.1287; 0.1532; 0.2134; 0.1048; 0.1248; 0.0806 | — |
Summary
The purpose of this study is to determine the effect of different amounts of time of morning light on brain emotional processing.
Eligibility Criteria
Inclusion Criteria
- Meets criteria for traumatic stress
- Normal or corrected to normal vision
- Right-handed
- Fluency in English
- Physically able to travel for study visit attendance
Exclusion Criteria
- Significant chronic uncontrolled disease (e.g. uncontrolled diabetes, advanced liver disease, cancer, etc.)
- Severe hearing problem
- Intellectual disability or serious cognitive impairment
- Inability to tolerate enclosed spaces (e.g. the MRI machine)
- Ferrous-containing metals within the body
- Pregnant, trying to get pregnant, or breastfeeding
- Epilepsy
- Other research participation
- Frequent number of special events during study period (weddings, concerts, exams, etc.)
Data sourced from ClinicalTrials.gov (NCT04117347). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.