N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
N/A N=23 Stress and the Nervous System
Autonomic Nervous System · Baroreflex · Stress, Physiological
Primary: Cardiovagal Baroreflex Sensitivity (Modified Oxford Technique) — 17.75; 16.90; 14.42; 17.27 ms/mmHg
Phase 2 N=121 Stress Management for Patients With Multiple Sclerosis
Multiple Sclerosis
Primary: No.of Gd+ Lesions From Week 8 to Week 24 — 46; 33; 5; 13 participants — p=0.04
N/A N=120 College Student Stress: Transitions Over Time
Depressive Symptoms
Primary: Percentage of Eligible Participants Who Agreed to Participate in the Trial — 120 Participants
N/A N=17 Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
Middle-aged Adults · Major Depressive Disorder
Primary: Nitric Oxide (NO)-Mediated Endothelium-dependent Dilation (EDD) — 70; 74 percentage — p=>0.05
Phase 4 N=226 Stress Neuroadaptation in Tobacco Dependence
Nicotine Dependence
Primary: Overall Stressor Reactivity — 25.1; 22.5; 32.3; 16.9 microvolts
N/A N=199 Caregiver Self-Management of Stress
Caregiver Distress · Job Stress
Primary: 10-item Kessler Psychological Distress Scale (K10) — 23.38; 23.79 score on a scale — p=0.513
N/A N=76 Stress and Sleep Study
Stress, Psychological · Sleep · Transcutaneous Electric Nerve Stimulation
Primary: Acceptability of the Combined tVNS + Mindfulness Intervention as Assessed by Participant Self-report of Acceptability Using the Acceptability of Intervention Measure…
N/A N=119 Stress Response in Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Negative Affect — 1.67; 1.25; 3.60 scores on a scale
N/A N=50 Stress and CKD Among African Americans
Chronic Kidney Disease
Primary: Change in Subjective Units of Distress Scale (SUDS) Score — 2.92; 3.12 score on a scale
N/A N=323 Stress, Salt Excretion, and Nighttime Blood Pressure
Blood Pressure · Psychological Stress
Primary: Ratio of Awake-to-asleep Urinary Sodium Excretion Rate (Aim 1) — 1.4 Ratio of awake-to-asleep — p=0.0032
N/A N=97 Influence of Stress on Encoding and Prediction
Stress · Learning, Spatial
Primary: Changes in fMRI Signal — 0.261; -0.264 Pearson's rho — p=0.023
Phase 4 N=84 Stress & Premenstrual Symptoms Study
PMDD · Stress · Mood
Primary: Acoustic Startle Response (ASR) Magnitude Based on Menstrual Cycle Phase — 54.2; 53.7; 56.4; 53.3 t score — p=0.139
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
N/A N=42 HEALTHY (Health Education Adolescent Leadership Training to Help Youth) Leaders
Stress
Primary: Number of Participants Reporting Pediatric Symptoms as Assessed by the Pediatric Symptom Checklist-17 (PSC-17) — 3; 2; 4; 3 participants
Phase 2 N=65 Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects
Acute Stress Reaction
Primary: Acute Stress Measured by Tension — 3089.4; 3253.4 mm*min — p=0.1233
N/A N=50 Comparison of Two Behavioral Treatments for Stress Reduction
Stress
Primary: Brain Activity (fMRI) During the Body Scan Meditation — 74; 82 voxels
Phase 2 N=66 Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects
Acute Stress Reaction
Primary: Acute Stress Measured by Tension — 3335.7; 3360.3 mm*min — p=0.7726
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
Phase 2 N=43 Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma
Asthma
Primary: Mean Score on the Family Asthma Management System Scale (FAMSS) — 4.9; 4.1 units on a scale — p=0.23
N/A N=120 Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
Healthy · Stress, Psychological
Primary: Change of the Heart Rate (HR) in Response to the Trier Social Stress Test (TSST) — 74.84; 74.34; 88.15; 86.69 bpm — p=0.757
N/A N=164 Mindful Hearts Study: Mindfulness to Reduce Stress
Cardiovascular Disease · Psychological Stress · Stroke
Primary: Perceived Stress — 15.94; 15.50 score on a scale
N/A N=49 Comparison of Two Programs for Weight Loss and Impact on Metabolic Syndrome
Metabolic Syndrome
Primary: Weight Loss — 1.6; 3.9 kg
N/A N=89 The Effects of a Music Intervention on Stress, Anxiety and Academic Performance on Nursing Students
Stress
Primary: Heart Rate Measurement — 83.45; 82.80; 81.88; 84.38 beats per minute
N/A N=93 Mindfulness-based Stress Reduction for Urban Youth
Stress, Psychological
Primary: Mindful Attention and Awareness Scale (MAAS) — 3.79; 3.66; 1.71; 1.56 units on a scale
N/A N=217 Breathe With Ease: A Unique Approach to Managing Stress (BEAMS)
Asthma
Primary: Symptom-free Days in the Last 14 Days — 11.4; 11.6 days in prior 14d — p=0.93
N/A N=13 Video Based Mindfulness Based Stress Reduction
Parkinson's Disease
Primary: Salivary Cortisol Levels (Pre- and Post-) Mindfulness-Based Stress Reduction Program — -33.1 Concentration (ng/mL)
N/A N=77 Stress, Emotion Regulation, and Alcohol in Women Veterans
Alcohol Use Disorder · Post Traumatic Stress Disorder
Primary: Change in Alcohol Craving During Experimental Sessions — 2.87; 2.97; 3.18; 3.22 Units on a Scale — p=.94