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N/A N=56 Randomized Double-blind Treatment

Refitting Frequent Replacement Lens Wearers Into Clariti 1 Day And 1-Day Acuvue Moist Daily Disposable Spherical Lenses

Myopia

Enrolled (actual)
56
Serious AEs
0.0%
Results posted
Aug 2020
Primary outcome: Primary: Lens Handling for Lens Insertion — 9.3; 8.0 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
somofilcon A (Device); etafilcon A (Device)
Age
Pediatric, Adult, Older Adult · 17+ yrs
Sex
All
Sponsor
CooperVision, Inc.
Primary completion
Feb 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Lens Handling for Lens Insertion
9.4; 8.1
PRIMARY
Lens Handling for Lens Insertion
9.4; 8.1
PRIMARY
Lens Handling for Lens Insertion
9.4; 8.1
PRIMARY
Lens Handling for Lens Insertion
9.4; 8.1
PRIMARY
Lens Handling for Lens Removal
9.4; 9.3
PRIMARY
Lens Handling for Lens Removal
9.4; 9.3
PRIMARY
Lens Handling for Lens Removal
9.4; 9.3
PRIMARY
Lens Handling for Lens Removal
9.4; 9.3
SECONDARY
Lens Centration
0.7; 0.8
SECONDARY
Lens Centration
0.7; 0.8
SECONDARY
Post-blink Movement
0.3; 0.3
SECONDARY
Post-blink Movement
0.3; 0.3
SECONDARY
Push-up Tightness
52; 48
SECONDARY
Push-up Tightness
52; 48

Summary

The objective of the study is to evaluate and compare the performance of somofilcon A to etafilcon A when worn on a daily disposable wear modality over a period of approximately one week.

Eligibility Criteria

Inclusion Criteria

  • Subjects will only be eligible for the study if:
  • Is at least 17 years of age and has full legal capacity to volunteer;
  • Has read and signed an information consent letter;
  • Is willing and able to follow instructions and maintain the appointment schedule;
  • Habitually wears silicone hydrogel frequent replacement soft contact lenses, for minimum of 6-months;
  • Is correctable to a visual acuity of 20/40 or better (in each eye) with the study lenses;
  • Can be fit with study contact lenses with a power between - 0.50 and -10.00 DS;
  • Demonstrates an acceptable fit with the study lenses;
  • Habitually wears contact lenses for at least 8 hours per day, and willing to wear contact lenses for at least 12 hours a day in the study.

Exclusion Criteria

  • Subjects will not be eligible to take part in the study if:
  • Is participating in any concurrent clinical or research study;
  • Has any known active* ocular disease and/or infection;
  • Has a systemic condition that in the opinion of the investigator may affect a study outcome variable;
  • Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
  • Has known sensitivity to the diagnostic pharmaceuticals to be used in the study;
  • Is pregnant, lactating or planning a pregnancy at the time of enrolment (verbal confirmation at the screening visit);
  • Is aphakic;
  • Has undergone refractive error surgery;
  • Is an employee of the Centre for Ocular Research & Education;
  • Has participated in the BEAGLE (EX-MKTG-104) study.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04195893). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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