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N/A N=72 Randomized Quadruple-blind Treatment

Pudendal Nerve Block in Vaginal Surgery

Nerve Block · Pain, Postoperative · Pelvic Floor Disorders · Pelvic Organ Prolapse · Pudendal Neuralgia

Enrolled (actual)
72
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Visual Analog Scores at 7am After Surgery — 29.2; 42.6 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Pudendal block (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
MetroHealth Medical Center
Primary completion
Sep 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Analog Scores at 7am After Surgery
29.2; 42.6
SECONDARY
Visual Analog Scores at Discharge From Post-anesthesia Care Unit
53.1; 56.4
SECONDARY
Pain Scores 96 Hours After Surgery
26.7; 35.5
SECONDARY
Quality of Recovery Scores on Post op Day 1 (7AM)
177.7; 172.3
SECONDARY
Satisfaction Scores in the Morning After Surgery (7AM)
81.5; 79.6
SECONDARY
Satisfaction Scores 96 Hours After Surgery
80.5; 79.4
SECONDARY
Opioid Analgesic Use in the Post-anesthesia Care Unit
5; 7.8
SECONDARY
Total Postoperative Opioid Use
15; 20.5
SECONDARY
Severity of Postoperative Non-pain Symptoms
37.2; 35.3
SECONDARY
Number of Participants With Postoperative Urinary Retention
7; 4

Summary

The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared to a sham pudendal nerve block in patients undergoing vaginal surgery.

Eligibility Criteria

Inclusion Criteria

  • Consenting, English speaking women between ages 18 and 80 who will undergo vaginal surgery
  • Ability to read VAS Scores
  • Specific vaginal procedures include, but are not limited to:

Perineoplasty Complete vaginectomy Le Forte colpocleisis Anterior repair, posterior repair, and/or enterocele repair Transvaginal mesh use Transvaginal mesh excision Sacrospinous ligament fixation Uterosacral ligament suspension Vaginal paravaginal defect repair Midurethral sling placement Sphincteroplasty Vaginal hysterectomy, with or without removal of tube(s) and/or ovary(s), with or without repair of enterocele

Exclusion Criteria

  • History of chronic pelvic pain
  • Currently taking sedatives
  • Liver disease
  • Renal disease
  • Women who did not consent for the study.
  • Intraoperative concern for increased blood loss
  • Unable to speak English
  • Unable to understand VAS Scores
  • Undergoing concomitant abdominal or laparoscopic procedures
  • Allergy to bupivacaine or triamcinolone
  • Planned abdominal or laparoscopic procedures.
  • Patients who are ineligible for non-narcotic pain medications, such as an allergy to acetaminophen or NSAIDs
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04198714). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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