N/A
Completed N=37
Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase
Substance Use Disorder · Opioid Use Disorder · Peer Delivered · Medication for Opioid Use Disorder (MOUD)
Source: ClinicalTrials.gov NCT04248933 ↗
Enrolled (actual)
37
Serious AEs
29.7%
Results posted
Dec 2022
Primary outcomePrimary: MOUD Retention Rate: % of Patients Retained at 3 Months — 31 Participants
Summary
The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) among low-income, minoritized individuals living with opioid use disorder (OUD) in Baltimore, Maryland. The intervention is based on behavioral activation (BA) and is specifically designed to be implemented by a trained peer recovery specialist. In this pilot trial, the investigators will evaluate the feasibility, acceptability, and fidelity of this approach (implementation outcomes) and preliminary effectiveness on methadone treatment retention at three months.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY MOUD Retention Rate: % of Patients Retained at 3 Months |
31 | — |
| PRIMARY Intervention Feasibility: % of Patients Who Agree to Participate in the Intervention |
32 | — |
| SECONDARY Intervention Acceptability: % of Patients Who Attend ≥75% Sessions |
26 | — |
| SECONDARY Intervention Fidelity: Percentage of Intervention Components Delivered by Peer as Intended |
87.9 | — |
Eligibility Criteria
Inclusion Criteria
- Initiated methadone at the study site or demonstrated challenges with methadone adherence in the past three months (e.g., at least one indicator of a missed methadone dose)
- Minimum of 18 years old
Exclusion Criteria
- Demonstrating active, unstable or untreated psychiatric symptoms, including mania and/or psychosis that would interfere with study participation
- Inability to understand the study and provide informed consent in English
- Positive pregnancy status at enrollment
Data sourced from ClinicalTrials.gov (NCT04248933). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.