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N/A N=40 Randomized Single-blind Basic Science

Daily Activity Study of Health: Increasing Physical Activity in Aging

Aging

Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Feb 2024
Primary outcome: Primary: Change in Sedentary Behavior (Average Hour/Day) — -0.11; 0.05 Change in average daily hours — p=0.8

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Motivational MRI and Behavioral Intervention (Behavioral); Control MRI and Behavioral Intervention (Behavioral)
Age
Adult, Older Adult · 60+ yrs
Sex
All
Sponsor
Northeastern University
Primary completion
Oct 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Sedentary Behavior (Average Hour/Day)
-0.11; 0.05 0.8
SECONDARY
Change in Moderate-to-Vigorous Physical Activity
-0.17; 0.14 0.35

Summary

In this six-week behavioral intervention, sedentary older adults will receive daily health messaging via their smart phone to better understand their daily activities and emotions. Participants undergo structural and functional brain imaging before and after the intervention along with measures of their behavioral, emotional and thinking functions.

Eligibility Criteria

Inclusion Criteria

  • Age range 60-95
  • Not exercising more than 150 minutes of moderate/vigorous intensity per week AND sitting more than 8 hours per day
  • No contraindications to MRI (if opting for MRI)
  • Being able to speak English fluently
  • Body Mass Index (BMI) between 20 and 40
  • Normal or corrected-normal vision based on the minimal 20/20 standard
  • Ambulatory without severe pain or the assistance of walking devices
  • No diagnosis of a neurological disease
  • Regular access to a computer with internet or smartphone

Exclusion Criteria

  • Primary care physician does not approve additional physical activity
  • Inability to ambulate without assistive device
  • Any unstable medical condition
  • Current diagnosis of a Diagnostic and Statistical Manual of Mental Disorders (DSM-V) Axis I or II disorder including Major Depression
  • History of major psychiatric illness including schizophrenia (not including general anxiety disorder or depression)
  • Current treatment for cancer - except non-melanoma skin
  • Neurological condition (multiple sclerosis, Parkinson's disease, dementia, mild cognitive impairment) or brain injury (traumatic or stroke)
  • Current alcohol or substance abuse
  • Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, deep vein thrombosis or other cardiovascular event
  • Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac condition in the past year
  • Not passing the Telephone Interview of Cognitive Status (TICS) as normal
  • Use of any anti-psychotic, anti-depressant, anti-anxiety, and attention deficit disorder (ADD/ADHD) medications.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04315363). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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