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N/A N=149 Randomized Single-blind Health Services Research

PEERS Using Peer Mentors to Deliver Depression Care

Depression

Bottom Line

View on ClinicalTrials.gov: NCT04319094 ↗
Enrolled (actual)
149
Serious AEs
3.4%
Results posted
Nov 2024
Primary outcome: Primary: Patient Health Questionnaire-9 — 6.66; 7.33; 7.89; 7.84 score on a scale — p=<0.0001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
PEERS (Behavioral); Social interaction (Other)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
Massachusetts General Hospital
Primary completion
May 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Patient Health Questionnaire-9		 6.66; 7.33; 7.89; 7.84; 7.95; 8.03 <0.0001 sig
SECONDARY
Rand Health Survey Short Form 36 - Physical Functioning		 47.64; 50; 50.12; 50.88; 43.48; 49.69 0.51
SECONDARY
Rand Health Survey Short Form 36 Item - Social Functioning		 60.29; 59.56; 64.29; 66.88; 59.47; 63.71 0.14
SECONDARY
Rand Health Survey Short Form 36 Item - Emotional Functioning		 44.44; 52.94; 49.21; 61.67; 48.96; 57.58 0.0129 sig
SECONDARY
Cornell Health Service Index - ER Service Use		 5; 8; 12; 2; 7; 7 0.031 sig
SECONDARY
Engagement - Adherence		 67; 62; 64; 61; 61; 60 —
SECONDARY
Working Alliance Inventory - Goal		 21.85; 23.17; 23.98; 25.05; 24.85; 25.1 —
SECONDARY
Working Alliance Inventory - Bond		 23.28; 24.49; 24.63; 25.02; 25.02; 25.45 —
SECONDARY
Working Alliance Inventory - Task		 21.24; 20.97; 22.67; 23.13; 23.03; 23.31 —
SECONDARY
UCLA Loneliness Scale		 51.54; 47.67; 44.56; 42.72; 43.9; 39.24 0.0005 sig
SECONDARY
General Self-Efficacy Scale		 27.98; 27.92; 27.93; 26.62; 26.15; 27.91 0.001 sig
SECONDARY
Brief COPE - Adaptive Coping		 44.12; 41.31; 44.5; 39.62; 42.7; 41.22 <0.0001 sig

Summary

Fifteen to twenty percent of older Americans (6 to 8 million people) suffer from depression but more than one-half do not receive any services, a burden disproportionately shared by low-income and minority older adults who receive few or no services. The investigators propose to test a community-based peer model of depression care called PEERS (a peer support program) that provides self-care support for minority and low-income older adults.

Eligibility Criteria

Inclusion Criteria

  • 50 years and older
  • depressive symptoms with Patient Health Questionnaire-9 scores ≥ 5
  • belong to an underserved population, defined as annual income less than 200% of the federal poverty level ($24,120) and/or self-identified ethnic minority
  • able to communicate in English
  • willing to give informed consent.

Exclusion Criteria

  • meet diagnostic criteria for mania or hypomania
  • meet diagnostic criteria for psychotic syndrome
  • meet diagnostic criteria for substance abuse or dependence
  • acutely suicidal
  • a score on the Mini-Mental State Examination (MMSE) ≤ 24
  • currently taking an antidepressant medication with dosage change in the past 3 months
  • receiving active psychotherapy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04319094). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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