N/A
N=5
Prism Adaptation in Left Brain Stroke
Aphasia · Spatial Neglect · Stroke
Bottom Line
View on ClinicalTrials.gov: NCT04387162 ↗Enrolled (actual)
5
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Client Satisfaction Questionnaire — 32; 27 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Prism Adaptation Treatment (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Jun 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Client Satisfaction Questionnaire |
32; 27 | — |
| PRIMARY Credibility/Expectancy Questionnaire |
6.2; 8.0; 56.7; 75.0 | — |
| PRIMARY Barthel Index |
70.8; 86.9; 75.0; 82.5; 71.7; 85.0 | — |
| PRIMARY Functional Independence Measure |
88.2; 97.7; 94.7; 98.5; 95.0; 99.5 | — |
| PRIMARY Behavioral Inattention Test- Conventional Subtest |
115.3; 120.4; 127.6; 119.0; 127.3; 123.5 | — |
| PRIMARY Catherine Bergego Scale Via the Kessler Foundation Neglect Assessment Process |
3.6; 3.2; 1.5; 1.5; 1.5; 2.5 | — |
| PRIMARY Wolf Motor Function Test |
35.5; 54.3; 35.7; 63.0; 35.0; 65.0 | — |
| PRIMARY Defense and Veterans Pain Rating Scale |
0.5; 3.7; 0.0; 3.5; 0.7; 1.5 | — |
| PRIMARY Classification of Lesion Location |
0; 0 | — |
Summary
Of the 15,000 Veterans who are hospitalized for stroke each year more than half experience spatial and motor impairments and pain. Spatial-motor-sensory problems limit functioning and independence, which is costly to Veterans, their families, and society. Currently, spatial-motor-sensory problems are targeted using different treatments. However, there is a treatment that has shown promise in simultaneously targeting spatial function, motor function and pain in right-brain stroke. The investigators propose to investigate the feasibility of using adapted spatial-motor sensory assessment and treatment procedures for Veterans with left-brain stroke who have language and cognitive impairment. The next step will be to conduct a large-scale study focused on this multi-target treatment for more efficient and effective stroke rehabilitation. The investigators expect this line of research to increase functioning, independence and quality of life in Veteran stroke survivors.
Eligibility Criteria
Inclusion Criteria
- 1-3 months post-stroke, entering outpatient treatment
- proficient English speakers
- experiencing moderate functional disability as measured by Functional Independence Measure (FIM), observational or telephone-administered FONE-FIM
- experiencing aphasia as determined by a Western Aphasia Battery Aphasia Quotient and memory impairment as determined by the Brief Visuospatial Memory Test- Revised, the Hopkins Verbal Learning Test- Revised or digit span forward and backward
- able to provide informed consent to participate, using aphasia-accessible process, as needed.
Exclusion Criteria
- History of brain conditions other than left brain stroke, including clinical right brain pathology.
Data sourced from ClinicalTrials.gov (NCT04387162). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.