N/A Completed N=60 Randomized Double-blind Treatment

Non-invasive Transcranial Electrical Stimulation in MS

Multiple Sclerosis · Mild Cognitive Impairment

Source: ClinicalTrials.gov NCT04466228 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2023

Primary outcomePrimary: Processing Speed Change From Baseline Assessment — 41.65; 42.05; 44.4; 46.1 score on a scale

Summary

The goal is to investigate the effects of non-invasive transcranial electrical stimulation on cognition in MS.

Outcome Measures

Outcome	Result	p-value
PRIMARY Processing Speed Change From Baseline Assessment	41.65; 42.05; 44.4; 46.1; 44.8; 44.8	—
PRIMARY EVO Performance Change From Baseline Assessment	—	—

Eligibility Criteria

Inclusion Criteria

age 18-65,
diagnosis of MS
Expanded Disability Status Scale (EDSS)≤6.5, no paresis of the upper limbs
a minimum of 3 months since the last relapse
Beck Depression Inventory<19
normal hearing
and no changes in MS or symptomatic medications in past 2 months

Exclusion Criteria

prior brain surgery
clips in brain
epilepsy or other neurological or non-affective psychiatric disorders
pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04466228). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.