N/A
Completed N=58
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Opioid Use Disorder · Adherence, Medication · HIV
Source: ClinicalTrials.gov NCT04479475 ↗
Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcomePrimary: Participants Who Attend Week 1 Intervention Session — 20; 28 Participants
Summary
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom. The B-SBNT involves families and the wider social networks of people receiving medications for opioid use disorder to support recovery. Key components of the intervention include: mapping the social networks of clients; inviting others identified through the mapping to participate in the intervention; building communication strategies with network members; and developing joint activities with network members. In the original B-SBNT, the intervention is delivered by therapists/clinicians who undergo training. Investigators will pilot test the adapted version of this intervention with a maximum of 80 people: 20 current clients receiving methadone maintenance treatment (MMT) at the Muhimbili National Hospital (MNH) Medically-Assisted Treatment (MAT) Clinic and up to 60 social support persons identified by recruited MMT clients. The pilot will assess the social network intervention's acceptability and feasibility.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Participants Who Attend Week 1 Intervention Session |
20; 28 | — |
| PRIMARY MMT Participants Who Attend Week 2 Intervention Session |
20 | — |
| PRIMARY Participants Who Attend Week 3 Intervention Session |
20; 25 | — |
| PRIMARY MMT Participants Who Attend Week 4 Intervention Session |
20 | — |
| PRIMARY Participants Who Attend Week 5 Intervention Session |
20; 25 | — |
| PRIMARY Participants Who Attend Week 6 Intervention Session |
20; 25 | — |
| PRIMARY Number of Intervention Counselors Who Adhered to the Intervention Manual |
5 | — |
| PRIMARY Number of Participants Who Find the Intervention Acceptable as Assessed by the Intervention Feasibility Interview |
10; 10; 5 | — |
| PRIMARY Intervention Acceptability Score |
2.77; 2.81 | — |
| SECONDARY Number of Missed Methadone Doses |
7.9 | 0.0094 sig |
| SECONDARY Participants Who Obtained All Prescribed ART Refills in Past 6 Months |
5; 5 | — |
Eligibility Criteria
Inclusion criteria for MMT client participants in the intervention pilot:
- 18 years old or older,
- currently enrolled in the MAT program at the Muhimbili MAT clinic,
- prescribed methadone for the past 3 months,
- received a positive test result for heroin, cannabis or alcohol use in the past 3 months,
- provide consent for trial participation.
Inclusion criteria for social support persons in the intervention pilot:
- 18 years old or older,
- identified as a social support person of a MMT client participating in the pilot trial
- lives in Dar es Salaam,
- provide consent for trial participation.
Exclusion Criteria
- Does not meet inclusion criteria
Data sourced from ClinicalTrials.gov (NCT04479475). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.