N/A
N=58
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Opioid-use Disorder · Adherence, Medication · HIV Infections
Bottom Line
View on ClinicalTrials.gov: NCT04479475 ↗Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Participants Who Attend Week 1 Intervention Session — 20; 28 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Supportive care through community support persons (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Primary completion
- Sep 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Participants Who Attend Week 1 Intervention Session |
20; 28 | — |
| PRIMARY MMT Participants Who Attend Week 2 Intervention Session |
20 | — |
| PRIMARY Participants Who Attend Week 3 Intervention Session |
20; 25 | — |
| PRIMARY MMT Participants Who Attend Week 4 Intervention Session |
20 | — |
| PRIMARY Participants Who Attend Week 5 Intervention Session |
20; 25 | — |
| PRIMARY Participants Who Attend Week 6 Intervention Session |
20; 25 | — |
| PRIMARY Number of Intervention Counselors Who Adhered to the Intervention Manual |
5 | — |
| PRIMARY Number of Participants Who Find the Intervention Acceptable as Assessed by the Intervention Feasibility Interview |
10; 10; 5 | — |
| PRIMARY Intervention Acceptability Score |
2.77; 2.81 | — |
| SECONDARY Number of Missed Methadone Doses |
7.9 | 0.0094 sig |
| SECONDARY Participants Who Obtained All Prescribed ART Refills in Past 6 Months |
5; 5 | — |
Summary
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom. The B-SBNT involves families and the wider social networks of people receiving medications for opioid use disorder to support recovery. Key components of the intervention include: mapping the social networks of clients; inviting others identified through the mapping to participate in the intervention; building communication strategies with network members; and developing joint activities with network members. In the original B-SBNT, the intervention is delivered by therapists/clinicians who undergo training. Investigators will pilot test the adapted version of this intervention with a maximum of 80 people: 20 current clients receiving methadone maintenance treatment (MMT) at the Muhimbili National Hospital (MNH) Medically-Assisted Treatment (MAT) Clinic and up to 60 social support persons identified by recruited MMT clients. The pilot will assess the social network intervention's acceptability and feasibility.
Eligibility Criteria
Inclusion criteria for MMT client participants in the intervention pilot:
- 18 years old or older,
- currently enrolled in the MAT program at the Muhimbili MAT clinic,
- prescribed methadone for the past 3 months,
- received a positive test result for heroin, cannabis or alcohol use in the past 3 months,
- provide consent for trial participation.
Inclusion criteria for social support persons in the intervention pilot:
- 18 years old or older,
- identified as a social support person of a MMT client participating in the pilot trial
- lives in Dar es Salaam,
- provide consent for trial participation.
Exclusion Criteria
- Does not meet inclusion criteria
Data sourced from ClinicalTrials.gov (NCT04479475). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.