N/A
Completed N=194
Moving Together: An Online Group Movement Program for People Living With Memory Loss and Caregivers
Source: ClinicalTrials.gov NCT04621448 ↗Enrolled (actual)
194
Serious AEs
6.2%
Results posted
Apr 2025
Primary outcomePrimary: Quality of Life - Change (Quality of Life in Alzheimer's Disease Scale, QOL-AD) — -1.7; 0.7 score on a scale — p=0.048
Summary
To determine whether Moving Together improves quality of life in people with memory loss (PWML) and caregivers (CG) by performing a randomized, controlled trial (RCT) with a waitlist control group in 224 dyads.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Quality of Life - Change (Quality of Life in Alzheimer's Disease Scale, QOL-AD) |
-1.7; 0.7 | 0.048 sig |
| PRIMARY Caregiver Physical Health - Change (Short Form Health Survey [SF-12] Physical Composite Score [PCS]) |
0.2; -0.6 | 0.603 |
| PRIMARY Caregiver Mental Health - Change (Short Form - 12 [SF-12] Mental Composite Score [MCS]) |
-0.7; 0.0 | 0.734 |
| SECONDARY Well-being - Change (Neuro-QOL v1.0 Positive Affect and Well-Being Short Form) |
-1.7; 0.1 | 0.159 |
| SECONDARY Social Isolation - Change (Patient-Reported Outcomes Measurement Information System v2.0 Social Isolation Scale) |
-0.2; -0.5 | 0.818 |
| SECONDARY Mobility - Change (Neuro-QOL Short Form V1.0 - Lower Extremity Function - Mobility) |
-1.6; 0.3 | 0.089 |
| SECONDARY Cognitive Function - Change (Telephone Montreal Cognitive Assessment, t-MoCA) |
-0.8; -0.5 | 0.631 |
| SECONDARY Caregiver Healthy Days - Change (Healthy Days Core Module) |
0.0; 0.5 | 0.484 |
| SECONDARY Caregiver Self-efficacy - Change (Gain in Alzheimer Care INstrument (GAIN)) |
0.1; 0.5 | 0.81 |
| SECONDARY Caregiver Burden - Change (Zarit Burden Interview, 6-item Version) |
-0.2; 0.4 | 0.384 |
| SECONDARY Caregiver Social Isolation - Change (PROMIS v2.0 Social Isolation Scale) |
0.3; -0.1 | 0.509 |
| SECONDARY Caregiver Self-regulation - Change (Abbreviated Multidimensional Assessment of Interoceptive Awareness-2 (MAIA) Self-regulation Subscale) |
0.3; 1.9 | 0.021 sig |
| SECONDARY Caregiver Positive Affect (Positive States of Mind) |
0.5; -0.3 | 0.156 |
| SECONDARY Caregiver Sleep - Change (Symptom Checklist, 3 Items) |
-0.1; 0.2 | 0.582 |
| SECONDARY People With Memory Loss (PWML) Sleep - Change (Symptom Checklist, 3 Items) |
0.1; -0.3 | 0.271 |
| SECONDARY People With Memory Loss (PWML) Mobility - Change (Neuro-QOL Short Form V1.0 - Lower Extremity Function - Mobility) |
-0.3; -0.2 | 0.834 |
| SECONDARY People With Memory Loss (PWML) Cognitive Function - Change (Cognitive Function Instrument - Modified) |
1.5; 1.8 | 0.529 |
Eligibility Criteria
Inclusion Criteria
- People with memory loss (PWML):
- U.S. resident;
- English language fluency;
- diagnosis of Alzheimer's disease or other dementia; mild severity, assessed using the Quick Dementia Rating System.
- Caregivers (CG):
- U.S. resident;
- English language fluency;
- Primary caregiver for PWML;
- own one or more devices that can be used to participate in two-way livestreaming video classes (e.g., smart phone/tablet + TV, laptop or desktop with webcam, smart TV);
- willing and able to participate in two-way livestreaming group movement classes with person with PWML.
Exclusion Criteria
- Age 1 week during initial 12-week study period.
Data sourced from ClinicalTrials.gov (NCT04621448). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.