N/A N=84 Randomized Basic Science

Mapping Aspects of Psychotherapy in Dialectical Behavior Therapy

Borderline Personality Disorder

Bottom Line

View on ClinicalTrials.gov: NCT04626310 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2024

Primary outcome: Primary: Change in Emotional Functioning - Linear — -.917; -1.25; -1.01 DERS scores/wk — p=.8

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Dialectical behavior therapy - emotion regulation skills training (Behavioral); Dialectical behavior therapy - interpersonal effectiveness skills training (Behavioral); Interpersonal psychotherapy (Behavioral)
Age: Adult · 18+ yrs
Sex: All
Sponsor: University of Massachusetts, Amherst
Primary completion: Feb 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Emotional Functioning - Linear	-.917; -1.25; -1.01	.8
PRIMARY Change in Borderline Personality Disorder Features - Linear	-1.716; -3.567; -3.667	.09
PRIMARY Change in Emotional Functioning - Quad	-.06; -.04; -.07	.762
PRIMARY Change in Borderline Personality Disorder Features - Quad	-.162; -.163; -.135	.93
SECONDARY Change in Self-reported Emotional Reactivity	-.07; -.09; -.12	.475
SECONDARY Change in Self-reported Emotional Regulation	-.18; -.01; .15	.001 sig
SECONDARY Change in Affect-modulated Startle	.015; .043; -.076	.13
SECONDARY Change in Emotional Habituation	-.156; .023; .134	.005 sig
SECONDARY Change in Physiological Emotional Reactivity	1.46; -.71; .41	.108
SECONDARY Change in Deliberate Physiological Emotional Regulation	.08; .10; .10	.211

Summary

Although dialectical behavior therapy (DBT) skills training is effective in the treatment of borderline personality disorder, it contains four skills modules and there is little research to guide their modular application. This study compares the unique effects of two distinct DBT skills training modules, relative to a non-DBT therapy group for adults with borderline personality disorder. Using innovative laboratory-based assessment methods, the proposed study will examine the effects of these conditions on emotional responding and interpersonal functioning, as well as clinical outcomes.

Eligibility Criteria

Inclusion Criteria

exhibit 4+ BPD symptoms,
have a history of recent (i.e., past-year) and recurrent (> 1 instance) of self-injury,
commit to participate in one of our 6-week experimental groups,
have an individual health provider who can manage imminent issues,
be between 18-60 years old,

Exclusion Criteria

not fluent in English,
have impaired (uncorrected) vision or hearing that would impair ability to understand study stimuli,
a current manic, psychotic, or active physiological dependence on substances (to limit interference in the lab),
low cognitive functioning (IQ ≤ 70.4 (TOPF; Pearson Assessments, 2009),
past DBT treatment

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04626310). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.