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Home › Conditions › borderline personality disorder

Borderline personality disorder

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for borderline personality disorder

18 trials tracked for borderline personality disorder: 4 in phase 3 or 4 and 4 with published results. The most-cited published study has 426 citations.

18Trials tracked
4Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 2 Phase 3 2 Phase 2 6 Other / NA 8
  1. Phase 4 Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder Completed · 426 cited
  2. Phase 4 Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder Completed · 120 cited
  3. Phase 3 Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD) Completed · 102 cited
  4. Phase 3 Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD) Completed · 2 cited
  5. Phase 2 A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder Completed
  6. Phase 2 Study to Test the Efficacy and Safety of Vafidemstat in Adult Borderline Personality Disorder Population Completed
Show 12 more trials
  1. Phase 2 A Trial of Brexpiprazole in the Treatment of Borderline Personality Disorder Completed
  2. Phase 2 Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms Completed
  3. Phase 2 Brexpiprazole in Borderline Personality Disorder Completed
  4. Phase 2 Caplyta in Borderline Personality Disorder Completed
  5. N/A Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder Completed
  6. N/A Isolating Mechanisms in the Treatment of Borderline Personality Disorder Completed
  7. N/A PET Imaging and Olanzapine Treatment in Borderline Personality Disorder Completed
  8. N/A Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder Completed
  9. N/A Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder Completed
  10. N/A Mapping Aspects of Psychotherapy in Dialectical Behavior Therapy Completed
  11. N/A Cognitive Reappraisal Training for Borderline Personality Completed
  12. N/A Treating Self Injurious Behavior: A Novel Brain Stimulation Approach Completed

Showing the 18 most-cited and recently-updated of 18 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Manualized psychological therapies yield small significant improvements in BPD symptom severity for adolescents
Psychiatry Meta-analysis
Manualized psychological therapies yield small significant improvements in BPD symptom severity for adolescents Manualized Psychological Therapies Show Small Gains for Adolescent BPD
This meta-analysis of 844 adolescents with Borderline Personality Disorder (BPD) found that manualized psychological therapies produced stat…
Specific psychological therapies show small but significant improvements in symptoms and emotion regulation for teens with Borderline Person…
Frontiers Jun 11, 2026
Comprehensive review of borderline personality disorder in East Asian adolescents highlights cultural context and treatment gaps
Oncology Sys. Review
Comprehensive review of borderline personality disorder in East Asian adolescents highlights cultural context and treatment gaps Borderline personality disorder affects some East Asian teens due to trauma and family issues
This comprehensive review examines borderline personality disorder among East Asian adolescents. The authors synthesize data showing prevale…
Borderline personality disorder shows up in 2% to 14% of East Asian teenagers. Childhood abuse and tough family situations often cause these…
Frontiers May 9, 2026
Qualitative review highlights barriers to recognizing autism in women with borderline personality disorder diagnoses
Psychiatry
Qualitative review highlights barriers to recognizing autism in women with borderline personality disorder diagnoses Many women with BPD may actually be autistic
This qualitative review synthesizes interviews with 15 clinicians and 15 women or people assigned female at birth regarding autism recogniti…
Hundreds of women told doctors they were misdiagnosed with borderline personality disorder when they may actually be autistic, raising urgen…
medRxiv Apr 29, 2026