N/A N=120 Randomized Single-blind Treatment

Laser Lithotripsy During URS - Holmium vs Thulium

Urolithiasis

Bottom Line

View on ClinicalTrials.gov: NCT04668586 ↗

Enrolled (actual)

120

Serious AEs

0.0%

Results posted

Mar 2025

Primary outcome: Primary: Stone Free Rate — 34; 47 Participants — p=<0.006

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Holmium:YAG laser machine (Device); Thulium Fiber laser machine (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Haukeland University Hospital
Primary completion: Jun 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Stone Free Rate	34; 47	<0.006 sig
SECONDARY Operating Time	60; 49	0.008 sig
SECONDARY Intraoperative Complications	0; 0	—
SECONDARY Postoperative Complications	8; 7; 6; 4; 2; 4	1
SECONDARY Postoperative JJ-stenting	31; 22	0.09

Summary

The aim of the study is to compare URS lithotripsy performed with Holmium:YAG laser and Thulium Fiber Laser. The study is designed as a prospective clinical randomised trial, where the study participants are randomised to either URS with Holmium:YAG laser or URS with Thulium Fiber Laser. The outcomes of the URS procedures are compared for the two treatment arms.

Eligibility Criteria

Inclusion Criteria

Patients planned for ureteroscopic treatment of ureteral and renal stones at the Day Surgery Unit at Haukeland University Hospital, Bergen, Norway

Exclusion Criteria

Known pathology of the upper urinary tract
Untreated infection

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04668586). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.