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Home › Conditions › urolithiasis

Urolithiasis

Subtypes of Urolithiasis

Bladder stones 1 Ureterolithiasis 1 Urinary Calculi 1

7 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for urolithiasis

12 trials tracked for urolithiasis: 3 in phase 3 or 4.

12Trials tracked
3Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 2 Phase 3 1 Phase 2 1 Other / NA 8
  1. Phase 4 Study of Tomography of Nephrolithiasis Evaluation Completed
  2. Phase 4 Vitamin D Repletion in Stone Formers With Hypercalciuria Completed
  3. Phase 3 Perioperative Pregabalin in Ureteroscopy: a Pilot Completed
  4. Phase 2 Study of Silodosin to Facilitate Passage of Urinary Stones Completed
  5. N/A Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE) Completed
  6. N/A CLinical Evaluation of Aspiration for Removal ANd ClearancE of Stones Completed
Show 6 more trials
  1. N/A Laser Lithotripsy During URS - Holmium vs Thulium Completed
  2. N/A Feasibility of Using sipIT Tools to Increase Compliance With Fluid Consumption Guidelines in Urolithiasis-Prone Subjects Completed
  3. N/A Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal Completed
  4. N/A Impact of Renal Anatomy on Shock Wave Lithotripsy Outcomes for Lower Pole Kidney Stones Completed
  5. N/A A Prospective Comparison of Fluoroscopic, Sonographic or Combined Approach for Renal Access in Percutaneous Nephrolithotomy Completed
  6. N/A Impact Ureteral Sheath Design During Ureteroscopy Completed

Showing the 12 most-cited and recently-updated of 12 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review and meta-analysis reports TFL lithotripsy complication rates in urolithiasis
Urology Meta-analysis
Systematic review and meta-analysis reports TFL lithotripsy complication rates in urolithiasis New laser tool breaks kidney stones with fewer serious side effects
This systematic review and meta-analysis of 3,329 patients with urolithiasis found a pooled overall complication rate of 10.42% for Thulium …
A new laser tool breaks kidney stones with fewer serious side effects and high success rates for most patients
May 12, 2026
Complication risks in elderly patients undergoing percutaneous nephrolithotomy compared to younger populations
Urology Meta-analysis
Complication risks in elderly patients undergoing percutaneous nephrolithotomy compared to younger populations Older patients can safely undergo kidney stone surgery with careful care
This systematic review and meta-analysis of 45,603 patients investigated complication rates and stone-free rates in elderly versus non-elder…
New research shows older adults can safely have kidney stone surgery, though infection risks rise with age.
May 7, 2026
Nomogram predicts bladder stone risk in BPH patients after prostate resection
Rheumatology Cohort
Nomogram predicts bladder stone risk in BPH patients after prostate resection New model predicts bladder stone risk in BPH patients after prostate surgery
This retrospective cohort study developed a nomogram to predict bladder stone risk in 446 BPH patients after transurethral resection.
A new tool helps doctors estimate bladder stone risk for men with enlarged prostates after surgery, based on a study of 446 patients.
Frontiers Apr 23, 2026
Progressive high-risk biological aging linked to increased urolithiasis risk in Chinese cohort
Diabetes & Endocrinology Cohort
Progressive high-risk biological aging linked to increased urolithiasis risk in Chinese cohort Your Aging Pattern Could Predict Kidney Stones
This observational cohort study of 27,948 participants found that a Progressive High-Risk biological aging trajectory was associated with an…
How fast your body ages, not just your calendar age, may be a hidden driver of painful kidney stones.
Frontiers Apr 19, 2026
Stepwise energy escalation ESWL showed higher stone-free rates than fixed-energy protocols in pediatric urolithiasis
Pediatrics Cohort
Stepwise energy escalation ESWL showed higher stone-free rates than fixed-energy protocols in pediatric urolithiasis A Gentler Way to Break Kidney Stones May Spare Children Extra Sessions
This single-center retrospective cohort study evaluated 81 children treated with extracorporeal shock wave lithotripsy (ESWL) for urolithias…
Slowly ramping up the energy used to shatter kidney stones in children appears to clear stones faster — and in fewer sessions — than the sta…
Frontiers Apr 13, 2026
Pilot RCT finds non-significant pain reduction with ESPB ropivacaine versus saline for ureteral stones
Anesthesiology & Pain Medicine RCT
Pilot RCT finds non-significant pain reduction with ESPB ropivacaine versus saline for ureteral stones Small pilot study tests nerve block for kidney stone pain in emergency department
A pilot randomized clinical trial of 24 ED patients with ureteral stones compared erector spinae plane block (ESPB) with ropivacaine 0.5% ve…
A small pilot study tested a nerve block injection for severe kidney stone pain in 24 emergency department patients.
Apr 7, 2026
Systematic review examines TCM and Western medicine enema therapies for urinary calculi
Urology Sys. Review
Systematic review examines TCM and Western medicine enema therapies for urinary calculi Review examines traditional Chinese and Western medicine enemas for urinary stones
A systematic review describes the mechanisms and clinical applications of traditional Chinese medicine and Western medicine enema therapies …
Enema therapy combining traditional Chinese and Western medicine may help manage urinary stones by targeting gut bacteria and reducing syste…
Frontiers Apr 3, 2026

Questions about urolithiasis

What is the overall complication rate for Thulium Fiber Laser lithotripsy in urolithiasis?

The pooled overall complication rate for Thulium Fiber Laser lithotripsy is about 10.4%, with major complications (Clavien-Dindo III-V) occurring in about 1.2% of cases.

Full answer →