Phase 4 N=512 Tamsulosin for Urolithiasis in the Emergency Dept
Ureterolithiases
Primary: Proportion of Patients Passing Their Stone Within 28 Days by Self Report — 128; 113 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=239 Study of Silodosin to Facilitate Passage of Urinary Stones
Ureteral Calculi · Kidney Stones · Urolithiasis
Primary: Spontaneous Stone Passage (Distal Stones) Without Need for Emergency Department Visits, Hospital Admissions, Surgical Intervention, or Other Interventional Procedures…
N/A N=100 Medical Expulsive Therapy of Single Distal Ureteral Stones
Ureteral Calculi
Primary: Number of Participants With Stone Expulsion — 39; 40 Participants
N/A N=1,658 Prevention of Urinary Stones With Hydration
Urinary Stones
Primary: Number of Participants With a Symptomatic Stone Event — 154; 165 Participants
N/A N=74 The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic
Ureteral Calculi
Primary: Time in Days From Diagnosis to Stone Passage. — 5; 13 Days
Phase 2 N=99 Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones
Hyperuricosuria · Kidney Stones
Primary: Percent Change From Baseline to Month 6 in 24-hour Urine Uric Acid (uUA) Excretion — -58.6; -36.4; -12.7 percent change — p=<0.001
Phase 4 N=2,776 Study of Tomography of Nephrolithiasis Evaluation
Urolithiasis
Primary: High Risk Diagnosis With Complication — 6; 3; 2 participants
N/A N=108 Trial Assessing Renal Damage During Ureteroscopy
Nephrolithiasis
Primary: Change in Kidney Injury Molecule-1 (KIM-1) — 0.01077; 0.01228; 0.0246; 0.02413 ng/ml
N/A N=127 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
Kidney Stones · Ureteral Stones
Primary: Stone Passage — 18; 21 participants
N/A N=53 Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
Kidney Stone
Primary: Time of Stone Passage — 68.8; 19.0 hours
N/A N=196 Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)
Urinary Stones
Primary: Number of Participants With Absence of or Have Residual Fragments Measuring Less </= to 2 mm — 41; 42 participants
Phase 2 N=16 Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria
Hyperoxaluria · Nephrolithiasis
Primary: Change From Baseline Period to Treatment Period 24-hour Urinary Oxalate Excretion — -13.92 mg/day
Phase 2 N=10 The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study
Cystinuria
Primary: 24hr Urine Measurements of the Effect of SGLT-2 Inhibitor Therapy on Cystine Production in Urine in Patients With Cystinuria — 999.3 24hr urine cystine concentration…
N/A N=104 Impact of Renal Anatomy on Shock Wave Lithotripsy Outcomes for Lower Pole Kidney Stones
Urolithiasis · Urinary Lithiasis · Kidney Calculi
Primary: Stone Clearance — 76 participants
Phase 3 N=19 Phentermine/Topiramate for Uric Acid Stones
Obesity · Uric Acid Stones · Type 2 Diabetes Mellitus in Obese
Primary: Kidney Stone Size (mm^3) Determined by Non-contrast CAT Scan — 6540; 4650; 3120; 5041 mm^3
Phase 2 N=33 Mirabegron as Medical Expulsive Therapy (MET) for Ureteral Stones and Ureteral Stent Pain
Ureteral Obstruction · Flank Pain
Primary: Spontaneous Stone Passage Using Fisher's Exact Test — 8; 5 Participants
N/A N=20 Utilizing Holmium Laser for FURS Renal Stone Lithotripsy Comparing Stone Breaking vs. Stone Dusting Settings
Stone Clearance
Primary: Stone Clearance — 6; 6; 3; 4 Participants
N/A N=13 Effect of Cola on Urinary Stone Risk Factors
Kidney Stone
Primary: The Plasma and Urine Parameters — 6800; 6800; 3700; 3700 mg per dL
N/A N=171 A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology
Nephrolithiasis
Primary: Operative Time — 36; 37 minutes
N/A N=58 Obesity and Endogenous Oxalate Synthesis
Obesity
Primary: Urinary Oxalate Excretion — 24 mg/day
Phase 2 N=13 Treatment for Calcium Phosphate Kidney Stone Disease
Calcium Phosphate Kidney Stones
Primary: Urinary Calcium Phosphate Saturation — 2.38; 1.97; 2.19 no units
Phase 4 N=114 Moses vs. Thulium Laser Study
Urinary Tract Stone
Primary: Procedural Time (Minutes) — 20; 17 minutes
N/A N=120 Laser Lithotripsy During URS - Holmium vs Thulium
Urolithiasis
Primary: Stone Free Rate — 34; 47 Participants — p=<0.006
N/A N=180 Comparing Treatment of Urolithiasis Between Disposable and Reusable Ureteroscope
Kidney Calculi · Ureter Calculi
Primary: Overall Procedure Time — 64.5; 54.1 minutes
N/A N=46 Effects of Flexible Ureteroscopy on Renal Blood Flow
Circulatory; Change
Primary: Peak Systolic Velocities (PSV) Measurement by Renal Doppler Ultrasound (US) Examination Evaluating the Effects of Flexible Ureteroscopy (F-URS) on Renal Blood Flow by…
Phase 2 N=20 Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones
Cystinuria · Nephrolithiasis, Calcium Oxalate
Primary: 24 Hour Urine Supersaturation of Calcium Oxalate (CaOx) — 1.83; 1.83; 1.87; 1.78 KJoules/mol — p=0.32
N/A N=219 Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
Renal Stone · Ureteral Stone
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS®) Scores of Pain-intensity at 7 to 10 Days — 4.28; 2.92 T-score — p=0.26
N/A N=70 Trial Comparing Dual Probe Ultrasonic Lithotripsy to a Single Probe Ultrasonic Lithotripsy
Kidney Stones
Primary: Kidney Stone Clearance Rate — 61.9; 75.8 mm^2/min
N/A N=82 Thulium vs. Hol:YAG Laser
Nephrolithiasis
Primary: Number of Participants With Stone Free Status — 27; 26 Participants
Phase 2 N=94 Toradol to Reduce Ureteroscopic Symptoms Trial
Urinary Lithiasis · Kidney Diseases · Kidney Stone
Primary: Post-operative Pain — 22; 30 milligram morphine equivalent