N/A
Completed N=5
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1
Source: ClinicalTrials.gov NCT04689867 ↗Enrolled (actual)
5
Serious AEs
0.0%
Results posted
Apr 2023
Primary outcomePrimary: Calgary Depression Rating Scale (CDRS) — 13.60; 9.00; 11.00; 7.60 score on a scale
Summary
The investigators are modifying and testing the preliminary effectiveness and implementation of a Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) intervention. In this phase of the study, CBSPp will be tested in an initial open trial (n = 10) to examine its feasibility and acceptability. Investigators will recruit clients receiving services at a community mental health setting who have a schizophrenia spectrum disorder and recent suicidal thoughts and behaviors to receive the behavioral intervention for 10-weeks. Providers will be recruited and trained to deliver the intervention. Both clients and providers will be assessed at baseline to test our approach to measurement prior to the Aim 2 RCT (registered separately). Clients will be assessed at three additional timepoints (middle of treatment, end of treatment, and 2 months after treatment ends.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Calgary Depression Rating Scale (CDRS) |
13.60; 9.00; 11.00; 7.60 | — |
| PRIMARY Positive and Negative Symptom Rating Scale (PANSS) |
20.20; 18.20; 42.40; 20.40; 19.00; 41.20 | — |
| PRIMARY Columbia-Suicide Severity Rating Scale (C-SSRS) |
3; 2; 3; 2; 0; 5 | — |
| SECONDARY Beck Hopelessness Scale |
12.80; 10.40; 12.00; 9.80 | — |
| SECONDARY The Entrapment Scale |
35.80; 30.40; 28.75; 36.0 | — |
| SECONDARY The Defeat Scale |
43.00; 40.40; 39.00; 41.5 | — |
Eligibility Criteria
Inclusion Criteria
- Schizophrenia Spectrum Disorder
- Suicide ideation and/or attempt within 3 months of screening
- Ability to speak and read in English
- 18 to 65 years of age
Exclusion Criteria
- Requiring emergency care (e.g. imminent plan to harm self) as determined by trained research staff administering the Columbia-Suicide Severity Rating Scale (C-SSRS)
- Inappropriate for behavioral treatment according to own judgment in consultation with a treating clinician CMH
- Impaired capacity (cognitive capacity)
Data sourced from ClinicalTrials.gov (NCT04689867). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.