N/A Completed N=498 Randomized Prevention

Leveraging Social Networks to Increase COVID-19 Testing Uptake

COVID · Substance Use Disorder · Opioid Use Disorder

Source: ClinicalTrials.gov NCT04873401 ↗

Enrolled (actual)

498

Serious AEs

0.0%

Results posted

Apr 2023

Primary outcomePrimary: Participants Who Agreed to Take a COVID-19 Rapid Test of Those Enrolled — 261; 214 participants who tested — p=0.928

Summary

This two-year project will adapt and conduct a trial examining the ability of two recruitment strategies, chain-referral and credible messenger, to reach those who use opioids and other substances in order to increase their uptake of onsite point of care COVID-19 testing that will be delivered in two community based organizations (CBOs): Alliance for Positive Change and Argus Health Inc. In Phase 1, Adapt two implementation strategies to support COVID-19 testing uptake and sustainability, adapting elements of existing efficacious social network-based interventions via a CBPR approach. In Phase 2, we will examine and compare the efficacy of two sets of implementation strategies on (i) reach, (ii) testing uptake, (iii) service delivery (i.e. quarantine, medical care, contact tracing) and (iv) sustainability for individuals who use opioids and other drugs. In Phase 3, Elucidate and compare the system/organizational-, staff-, and individual-level factors that influence implementation (i.e. fidelity, acceptability, feasibility, sustainability) of the strategies to develop a plan for dissemination and scale-up in other CBOs who serve opioid and other substance using individuals in NYC.

Outcome Measures

Outcome	Result	p-value
PRIMARY Participants Who Agreed to Take a COVID-19 Rapid Test of Those Enrolled	261; 214	0.928
PRIMARY Mean Number of COVID-19 Rapid Tests Taken	1.8; 1.6	0.240
PRIMARY Uptake of the Recruitment Strategy Into the Community	271; 227	0.367
PRIMARY Reach of the Recruitment Strategy Into the Community	624; 468	0.005 sig
SECONDARY Participant Acceptability of Recruitment Strategy and Testing Program Scale	—	—
SECONDARY Sustainability of the Testing Program	—	—
SECONDARY Feasibility of Recruitment and Testing Protocols	—	—

Eligibility Criteria

Inclusion Criteria

Endorse opioid use in the past 6 months
Speak English or Spanish
Age 18+

Exclusion Criteria

Deny history of opioid use (but will be offered COVID-19 testing)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04873401). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.