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N/A N=106 Randomized Treatment

Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents

Depressive Symptoms · Depression · Adolescent Behavior

Enrolled (actual)
106
Serious AEs
0.0%
Results posted
Jun 2024
Primary outcome: Primary: Mean Score of Depressive Symptoms — -9.50; -8.30 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Behavioral Activation Therapy app (Behavioral); Treatment as Usual (Behavioral)
Age
Pediatric, Adult · 16+ yrs
Sex
All
Sponsor
Medical University of South Carolina
Primary completion
May 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Score of Depressive Symptoms
-9.50; -8.30
PRIMARY
Average Vapes Per Day at Week 4
9.42; 10.17
PRIMARY
E-cigarette Dependence
-2.19; -2.38
PRIMARY
Number/Duration of Quit Attempts
5.00; 4.00
PRIMARY
7-day Point Prevalence Abstinence
14; 15

Summary

The purpose of this study is to evaluate a mobile application (app) called "Goal2QuitVaping" to help adolescents quit vaping nicotine. Goal2QuitVaping was developed by our research team to assist with quitting vaping. Participants will be randomly assigned to either download the mobile app, "Goal2QuitVaping", or not. If provided with Goal2QuitVaping, participants will be asked to use the app regularly, at least once per day, throughout the study duration. Participants will be asked to complete electronic questionnaire measures throughout the study period. Participation in this study will take about 4 weeks.

Eligibility Criteria

Inclusion Criteria

  • age 16-20
  • vaped nicotine on ≥20 days out of the last 30
  • elevated depressive symptoms, defined as a score of ≥10 on Patient Health Questionnaire-8 (PHQ-8) during preliminary screening and the Adolescent Patient Health Questionnaire-9 (PHQ-9A) at final eligibility
  • currently own an iOS or Android smartphone
  • report willingness to utilize an app for quitting vaping nicotine (response of "yes" on yes/no item)
  • have a valid e-mail address that is checked regularly or regular access to text messages (for follow-up assessments)
  • ability to read the consent form
  • has been seen (in person or remotely) by a primary care physician within the last year

Exclusion Criteria

  • smoked cigarettes or used other tobacco products on ≥9 days out of the last 30
  • severe visual impairment
  • currently receiving treatment for vaping or tobacco use
  • current suicidal ideation, defined as a response ≥1 on item nine of the PHQ-9A or ≥2 on item 9 of the BDI-II
  • household member currently enrolled in the study
  • inability to read the consent form
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04951193). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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