N/A
N=36,104
Mental Health Associations With Vitiligo
Vitiligo · Depressive Episode · Recurrent Depressive Disorder · Anxiety Disorders · Social Phobia
Bottom Line
View on ClinicalTrials.gov: NCT04953338 ↗Enrolled (actual)
36,104
Serious AEs
—
Results posted
Dec 2025
Primary outcome: Primary: Number of Participants With Depressive Episodes — 1018; 4007 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Exposure of mental health condtion of interest (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Momentum Data
- Primary completion
- Aug 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Depressive Episodes |
1018; 4007 | — |
| PRIMARY Risk of Depressive Episodes Within Adult Patients With Vitiligo |
157; 501 | — |
| PRIMARY Number of Participants With Anxiety Disorder |
569; 2031 | — |
| PRIMARY Number of Participants With Recurrent Depressive Disorder |
1093; 4305 | — |
| PRIMARY Risk of Anxiety Disorder Within Adult Patients With Vitiligo |
122; 382 | — |
| PRIMARY Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo |
113; 312 | — |
Summary
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with vitiligo compared to controls and to evaluate whether the relative risks may vary by different ethnicity.
Eligibility Criteria
Inclusion Criteria
- All eligible adults ≥18 (as at date of vitiligo diagnosis for cases or start of follow-up for controls) registered with GP practices contributing data to OPCRD between January 1, 2004 and December 31, 2020, were eligible for inclusion in the study.
Exclusion Criteria
- People with less than 1 year of follow up available
Data sourced from ClinicalTrials.gov (NCT04953338). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.