N/A
N=240
Opioid Use After Thyroid and Parathyroid Surgeries
Thyroidectomy · Parathyroidectomy · Opioid Use · Pain, Postoperative
Bottom Line
View on ClinicalTrials.gov: NCT04955444 ↗Enrolled (actual)
240
Serious AEs
—
Results posted
Sep 2023
Primary outcome: Primary: New Opioid Discharge Prescriptions — 128; 28 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Quality improvement bundle (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- The Methodist Hospital Research Institute
- Primary completion
- Dec 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY New Opioid Discharge Prescriptions |
128; 28 | — |
| SECONDARY Opioid Discharge Prescriptions Exceeding 112.5 Oral Morphine Milligram Equivalents (MMEs) |
52; 8 | — |
| SECONDARY Opioid Discharge Prescriptions Exceeding 5 Days |
27; 5 | — |
| SECONDARY New Opioid Prescriptions From the Surgeon's Office Within 7 Days of Surgery |
0; 0 | — |
| SECONDARY Opioid Prescriptions Exceeding 50 Oral MMEs/Day When New Discharge Prescriptions Are Added to Existing Opioid Therapy |
9; 0 | — |
Summary
Unnecessary opioid prescriptions for postoperative pain can increase the risk for new, persistent opioid use and dependence. Published literature suggests that most patients undergoing thyroid or parathyroid surgery can have their pain effectively managed without opioids following hospital discharge. The purpose of this quasi-experimental, quality improvement study is to develop, implement, and measure the impact of a quality improvement bundle that consists of (1) patient education, (2) provider education, and (3) electronic health record (EHR) enhancements. The proportion of patients who receive new opioid discharge prescriptions for pain management following thyroid or parathyroid surgery at Houston Methodist Hospital for up to 6 months following bundle implementation will be compared to a historical control group.
Eligibility Criteria
Inclusion Criteria
- Adult patients undergoing a primary thyroidectomy or parathyroidectomy procedure at Houston Methodist Hospital during the study period. Only index surgeries during the study time frame were included.
Exclusion Criteria
- Patients with a hospital length of stay after surgery >2 days
Data sourced from ClinicalTrials.gov (NCT04955444). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.