N/A
N=754,745
The Incidence of Venous Thromboembolism in Atopic Dermatitis
Venous Thromboembolism · Atopic Dermatitis · Pulmonary Embolism · Deep Vein Thrombosis · Allergic Rhinitis
Bottom Line
View on ClinicalTrials.gov: NCT04969653 ↗Enrolled (actual)
754,745
Serious AEs
—
Results posted
Dec 2024
Primary outcome: Primary: Number of Participants With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person. — 2576; 7563 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Exposure of venous thromboembolism (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Momentum Data
- Primary completion
- Mar 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person. |
2576; 7563 | — |
| SECONDARY Number of Participants With Diagnosis of Pulmonary Embolism After the Start of Follow-up for Each Person |
797; 2942 | — |
| SECONDARY Number of Participants With Diagnosis of Deep-vein Thrombosis After the Start of Follow-up for Each Person |
1887; 4934 | — |
| SECONDARY Number of Male Participants With Diagnosis of Risk of Venous Thromboembolism After the Start of Follow-up for Each Person |
1070; 3170 | — |
| SECONDARY Number of Female Participants With Diagnosis of Risk of Venous Thromboembolism After the Start of Follow-up for Each Person |
1506; 4393 | — |
| SECONDARY Number of Participants Aged 18-44 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
503; 1592 | — |
| SECONDARY Number of Participants Aged 45-64 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
639; 1858 | — |
| SECONDARY Number of Participants Aged ≥65 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
1434; 4113 | — |
| SECONDARY Number of Participants BMI <30 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
1398; 3188 | — |
| SECONDARY Number of Participants BMI ≥30 With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
685; 760 | — |
| SECONDARY Number of Female Participants Aged 18-44 Using Oestrogen Contraceptive With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
31; 34 | — |
| SECONDARY Number of Participants Having History of an Allergic Condition With Diagnosis of Venous Thromboembolism After the Start of Follow-up for Each Person |
193; 203 | — |
Summary
This study aims to investigate the incidence of venous thromboembolism in people who are diagnosed with atopic dermatitis.
Eligibility Criteria
Inclusion Criteria
- All eligible adult people (aged ≥ 18) registered with GP practices contributing data to OPCRD between January 1, 2010 and January 1, 2020, were eligible for inclusion in the study.
Exclusion Criteria
- People with less than 5 years potential follow up. People with atopic dermatitis that was not active atopic dermatitis during the study period. People without atopic dermatitis but diagnosed with other skin conditions.
Data sourced from ClinicalTrials.gov (NCT04969653). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.