N/A N=57 Randomized Single-blind Treatment

Improving Depression Management

Depression

Bottom Line

View on ClinicalTrials.gov: NCT05050227 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2024

Primary outcome: Primary: Patient Health Questionnaire (PHQ-9) — 12.6; 15.2 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: cCBT Enhanced Collaborative Care (Behavioral); Usual Care (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: VA Office of Research and Development
Primary completion: Jun 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Patient Health Questionnaire (PHQ-9)	12.6; 15.2	—
SECONDARY PROMIS Global Health	38.3; 38.7; 36.9; 38.2	—
SECONDARY Generalized Anxiety Disorder (GAD-7)	9.6; 10.6	—
SECONDARY Patient Activation Measure (PAM)	37.5; 38.6	—
SECONDARY PTSD Checklist for DSM-5 (PCL-5)	30.1; 34.0	—
SECONDARY Behavioral Activation for Depression Scale (BADS-SF)	21.4; 22.6	—

Summary

Depression is disabling and affects one in five Veterans. VA's Primary Care-Mental health Integration (PC-MHI) enables specialists to support medication treatment in primary care, but timely and sufficient access to psychotherapy is unattainable despite Veteran preference for psychotherapy. This study aims to close the gap in psychotherapy access for VA primary care patients with depression by adapting and pilot testing PC-MHI collaborative care models to improve uptake of computerized cognitive behavioral therapy (cCBT).

Eligibility Criteria

Inclusion Criteria

Have access to computer (mobile or desktop), internet, telephone, and email
Able to read English text on a computer screen
Score 10 or higher on the PHQ-9

Exclusion Criteria

Have moderate-high suicide risk (e.g., suicide flag) or active suicidality
Have other serious mental illness (e.g. bipolar disorder, psychosis)
Have medical disorder that would prevent/interfere with participation (e.g. dementia/cognitive impairment, terminal illness)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05050227). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.