N/A
N=82
Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa
Substance-Related Disorders · Mental Disorder · Social Stigma · Depression · Treatment Adherence and Compliance
Bottom Line
View on ClinicalTrials.gov: NCT05282173 ↗Enrolled (actual)
82
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: CHW Stigma Towards Substance Use — -0.88 change in units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Siyakhana CHW Training (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Maryland, College Park
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY CHW Stigma Towards Substance Use |
-1.22 | — |
| PRIMARY CHW Stigma Towards Depression |
0.51 | — |
| PRIMARY Training Feasibility |
26; 25; 27 | — |
| PRIMARY Acceptability |
2.92; 2.84; 2.80 | — |
| PRIMARY CHW Training Fidelity |
86.7; 85.7; 82.7 | — |
| SECONDARY CHW Stigma Towards Substance Use |
-1.22 | — |
| SECONDARY CHW Stigma Towards Depression |
0.51 | — |
Summary
Poor engagement in care contributes to HIV- and TB-related morbidity and mortality in South Africa (SA). Community health workers (CHWs) are frontline lay health workers who work to re-engage patients who are lost to follow-up (LTFU) in HIV/TB care. Patients with depression and substance use (SU) have a greater likelihood of being LTFU in HIV/TB care, and there is evidence that CHWs may exhibit stigma towards these patients. When CHWs have negative attitudes towards these patients, on average they spend less time with these patients, are less likely to implement evidence-based practices, and deliver less patient-centered care. Therefore, this purpose of this study is to examine the implementation and preliminary effectiveness of a brief training ("Siyakhana"). The purpose of this training is to provide CHWs with psychoeducation, skills, and support around working with HIV/TB patients with depression/SU. The investigators will assess the training's implementation and changes in CHWs' stigma towards HIV/TB patients with depression/SU.
Eligibility Criteria
Inclusion Criteria
- At least 18 years old
- Employed as a CHW through a partner non-governmental organization (NGO) that provides HIV/TB CHW services
- Works with patients who have HIV and TB, some of whom may be struggling with depression or substance use
Exclusion Criteria
- Unable to complete informed consent or study procedures in English or Xhosa
Data sourced from ClinicalTrials.gov (NCT05282173). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.