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N/A Completed N=38 Randomized Double-blind Treatment

Clinical Evaluation of Two Silicone Hydrogel Contact Lenses

Source: ClinicalTrials.gov NCT05313412 ↗
Enrolled (actual)
38
Serious AEs
0.0%
Results posted
May 2023
Primary outcomePrimary: Ease of Lens Insertion — 92.1; 90.9 units on a scale

Summary

This study is to compare the short-term clinical performance and subjective acceptance of two silicone hydrogel soft contact lenses.

Outcome Measures

OutcomeResultp-value
PRIMARY
Ease of Lens Insertion
92.1; 90.9

Eligibility Criteria

Inclusion Criteria

  • They are aged between 18 and 40 years.
  • They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent.
  • They are willing and able to follow the protocol.
  • They have successfully worn contact lenses within six months of starting the study.
  • They can be satisfactorily fitted with the study contact lenses.
  • They have a contact lens spherical prescription between -0.25 to - 6.00D (inclusive) based on the ocular refraction.
  • They have a spectacle cylindrical correction of -0.75D or less in each eye based on the ocular refraction.
  • They own and habitually wear single vision spectacles.
  • They can attain at least 0.20 logMAR distance high contrast visual acuity in each eye, with the study lenses.
  • They agree not to participate in other clinical research while enrolled on this study.

Exclusion Criteria

  • They have an ocular disorder which would normally contraindicate contact lens wear.
  • They have a systemic disorder which would normally contraindicate contact lens wear.
  • They are using any topical medication such as eye drops or ointment.
  • They are aphakic.
  • They have had corneal refractive surgery.
  • They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.
  • They are pregnant or breastfeeding.
  • They have any ocular abnormality which would, in the opinion of the investigator, normally contraindicate contact lens wear or pose a risk to study personnel; or they have any immunosuppressive disease (eg HIV) or a history of anaphylaxis or severe allergic reaction.
  • They have grade 3 or greater of any of the following ocular surface signs: corneal oedema, corneal vascularisation, corneal staining, tarsal conjunctival changes or any other abnormality, which would normally contraindicate contact lens wear.
  • They have taken part in any other clinical trial or research, within two weeks prior to starting this study, which may impact on this particular work.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05313412). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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