N/A Completed N=45 Treatment

The BRAIN App: Building Relationships Using Artificial Intelligence and Nostalgia

Dementia · Dementia, Vascular · Alzheimer's Disease · Dementia, Mixed

Source: ClinicalTrials.gov NCT05515679 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2024

Primary outcomePrimary: Change From Baseline to Treatment for Constructive Engagement on the Menorah Park Engagement Scale — .72 score on scale — p=<0.01

Summary

This study will involve testing of an Alpha version of an app called "Building Relationships using Artificial Intelligence and Nostalgia" or BRAIN. The BRAIN App will be the first -ever artificial intelligence infused CST app for PWD. The app has two main goals: (1) to foster positive relationships between the care triad, and (2) to promote QoL while reducing responsive behaviors in PWD. Testing will examine the app's impact on engagement/affect for both PWD and professional Care Partners.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change From Baseline to Treatment for Constructive Engagement on the Menorah Park Engagement Scale	.72	<0.01 sig
PRIMARY Change From Baseline to Treatment for Passive Engagement on the Menorah Park Engagement Scale	-0.33	.017 sig
PRIMARY Change From Baseline to Treatment for Other Engagement on the Menorah Park Engagement Scale	-.25	.008 sig
PRIMARY Change From Baseline to Treatment for Non-Engagement on the Menorah Park Engagement Scale	-0.15	0.053
PRIMARY Change From Baseline to Treatment for Pleasure on the Menorah Park Engagement Scale	.66	<.01 sig
PRIMARY Change From Baseline to Treatment for Positive Items Sub-score on the Engagement of Persons With Dementia Scale (EPWDS)	4.11	<.001 sig
PRIMARY Change From Baseline to Treatment for Negative Items Sub-score on the Engagement of Persons With Dementia Scale (EPWDS)	-1.07	<.001 sig
SECONDARY Change From Baseline to Treatment on Dementia Related Quality of Life (DEMQOL)	6.02	.022 sig
SECONDARY Change From Baseline to Treatment on the Neuropsychiatric Inventory-Nursing Home (NPI-NH), Frequency x Severity Score (FxS)	1.23	.551
SECONDARY Change From Pre-Test to Post-Test for the Knowledge Assessment for BRAIN Training for Staff	27.43	<.001 sig
SECONDARY Percent of Staff Who Thought Residents Enjoyed BRAIN Activities	100	—
SECONDARY Percent of Staff Who Said They Would Recommend the BRAIN App to Colleagues	100	—
SECONDARY Percent of Staff Who Said They Thought the BRAIN App Would Improve Quality of Life of Persons With Dementia.	100	—

Eligibility Criteria

PWD Inclusion Criteria:

diagnosed with dementia (any type)
resident in ALF or NH
65+ years old
read and speak English
exhibit at least one responsive behavior on the NPI-NH or score below maximum score on the DEMQOL

PWD Exclusion Criteria:

bed-confined
completely unable to communicate verbally
have serious visual or hearing impairments
show signs of rapid decline or over the last six months

Staff and Family Member Inclusion Criteria

18+ years old
speak and read English

Staff and Family Member Exclusion Criteria

-n/a

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05515679). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.