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N/A N=194,238 Randomized Single-blind Health Services Research

Patient Portal Flu Vaccine Reminders_RCT 5 (LADHS)

Influenza · Respiratory Tract Infections

Enrolled (actual)
194,238
Serious AEs
Results posted
Apr 2025
Primary outcome: Primary: Receipt of the Annual Influenza Vaccine Among Adult and Pediatric Index Patients — 4641; 4629; 120137 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Enhanced texts with Callback by a Person (Behavioral); Enhanced Bidirectional Texts (Behavioral)
Age
Pediatric, Adult, Older Adult · 0+ yrs
Sex
All
Sponsor
University of California, Los Angeles
Primary completion
Mar 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Receipt of the Annual Influenza Vaccine Among Adult and Pediatric Index Patients
4641; 4629; 120137
SECONDARY
Receipt of the Annual Influenza Vaccine Among Pediatric Index Patients

Summary

This trial is taking place in Los Angeles, CA at clinics within the Los Angeles Department of Health clinics. The study design is a comparative effectiveness trial design. Patients will be randomized into 1) receiving enhanced texting with a callback by a trained call-center staff member to schedule a vaccine visit if the patient presses "1" in response to the text, 2) receiving enhanced bidirectional texting with a texting response from a trained call-center staff member who will help the patient schedule a vaccine visit through a series of back-and-forth texts, or 3) standard text reminders (control group). Patients in all arms will receive reminders if they are due for influenza vaccine. Despite the Advisory Committee on Immunization Practices (ACIP) recommendation in 2010 that all people above 6 months of age should receive an annual flu vaccine, vaccination rates remain low: at 6m-4.9 yrs. (70%), 5-17.9 yrs. (56%), 18-64.9 yrs. (38%), and >65 yrs. (63%). The investigators will assess the effectiveness of enhanced text R/R messages as compared to the standard of care control (standard text reminders).

Eligibility Criteria

Inclusion Criteria

  • LADHS patients identified as primary care patients assigned as follows: (1) assigned through managed care plans, (2) self-pay but linked with a provider, or (3) uninsured but assigned.

Exclusion Criteria

  • LADHS patient not identified as a primary care patient.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05535777). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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