N/A
Completed N=206
Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults
Obesity · Overweight · Overweight and Obesity
Source: ClinicalTrials.gov NCT05625061 ↗
Enrolled (actual)
206
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcomePrimary: Met Daily Weighing Goal — 4399; 4167; 1496; 1393 goals met — p=.03
Summary
The purpose of this micro-randomized trial is to evaluate the effects of 7 types of intervention messages targeting specific behavior change techniques (i.e., BCT messages) delivered in "just-in-time" (JIT) moments on daily achievement of weight-related behavioral goals among n=201 young adults with overweight and obesity, participating in a digital, mobile comprehensive lifestyle intervention. "Just-in-time adaptive interventions" (JITAIs) are an alternative to the "one size fits all" approach of mobile intervention development that can provide tailored, real-time messaging and support for young adults.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Met Daily Weighing Goal |
4399; 4167; 1496; 1393; 249; 226 | .03 sig |
| PRIMARY Met Daily Active Minutes Goal |
8781; 8727; 2905; 2959; 473; 456 | 1.00 |
| PRIMARY At or Under Daily Red Foods Limit |
13080; 12848; 4385; 4261; 724; 711 | .02 sig |
| SECONDARY Weight Change |
-2.45 | < .0001 sig |
| SECONDARY Percent Weight Change |
-2.65 | < .0001 sig |
| SECONDARY Proportion of Days Met Daily Weighing Goal |
0.585 | < .0001 sig |
| SECONDARY Proportion of Daily Active Minutes Goal Met |
0.795; 0.802; 0.789; 0.808; 0.762; 0.803 | .43 |
| SECONDARY Proportion of Daily Red Foods Limit |
1.042; 1.050; 1.040; 1.052; 1.017; 1.055 | 1.00 |
| SECONDARY Number of Active Minutes |
29.05; 29.44; 28.86; 29.61; 27.36; 28.08 | .12 |
| SECONDARY Number of Red Foods |
3.45; 3.47; 3.45; 3.47; 3.39; 3.48 | 1.00 |
| SECONDARY Met Daily Weighing Goal Tomorrow |
29985; 29969; 10022; 9959; 1637; 1682 | 1.00 |
| SECONDARY Met Daily Active Minutes Goal Tomorrow |
13415; 13472; 4452; 4501; 709; 670 | 1.00 |
| SECONDARY At or Under Daily Red Foods Limit Tomorrow |
12875; 12793; 4245; 4312; 680; 674 | .51 |
Eligibility Criteria
Inclusion Criteria
- Body mass index (BMI) of 25 - 45 kg/m^2 at baseline
- English-speaking, reading, and writing
- Own a smartphone with a data and text messaging plan
Exclusion Criteria
- Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
- Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q; items 1-4).
- Other health problems which may influence the ability to walk for physical activity or be associated with unintentional weight change, including cancer treatment within the past 5 years or tuberculosis
- Lost 10 lbs. or more of body weight (and kept it off) in the last 6 months
- Past diagnosis of or receiving treatment for a clinically diagnosed eating disorder (anorexia nervosa or bulimia nervosa)
- Current symptoms of alcohol or substance dependence
- Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 6 months
- Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
- Hospitalization for depression or other psychiatric disorder within the past 12 months
- History of psychotic disorder or bipolar disorder
- Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study
- Currently using prescription medications with known effects on appetite or weight (e.g., oral steroids, weight loss medications), with the exception of individuals on a stable dose of Selective Serotonin Reuptake Inhibitors (SSRIs) for 3 months)
- Previous surgical procedure for weight loss or planned weight loss surgery in the next year
- Another member of the household is a participant or staff member on this trial
- Reason to suspect that the participant would not adhere to the study intervention
- Reside outside of the United States
- Have participated in another study conducted by the UNC Weight Research Program within the past 12 months
Data sourced from ClinicalTrials.gov (NCT05625061). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.