N/A N=21 Prevention

A Prenatal Bonding Intervention for Pregnant Women With Depression

Depression · Pregnancy

Bottom Line

View on ClinicalTrials.gov: NCT05628675 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2025

Primary outcome: Primary: Change on Maternal Antenatal Attachment Scale (MAAS) — 69.7; 72.4; 75.9 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Baby CHAT (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: Female
Sponsor: King's College London
Primary completion: Jul 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Change on Maternal Antenatal Attachment Scale (MAAS)	69.7; 72.4; 75.9	—
SECONDARY Change on Prenatal Parental Reflective Functioning Questionnaire (P-PRFQ)	60.7; 65.7; 67.1	—
SECONDARY Change on Edinburgh Postnatal Depression Scale (EPDS)	17.3; 12.1; 10.4	—

Summary

The goal of this clinical trial is to test a group for pregnant women with depression that aims to help them build a stronger relationship with their unborn baby. The main questions it aims to answer are: * Is the group acceptable to pregnant women with depression? * Is it possible to run this group with pregnant women with depression? * Could the group potentially impact bonding, parental reflective functioning and mood? Participants will be asked to: * attend the group (which lasts 90mins) * complete questionnaires before and after the group, and 1 month later

Eligibility Criteria

Inclusion Criteria

Currently pregnant
Aged ≥18 years
Between 20- and 34-weeks' gestation
Currently experiencing depressive symptoms as identified by the Edinburgh Postnatal Depression Scale (EPDS)
Resident in or accessing services in a London borough served by South London & Maudsley NHS Foundation Trust

Exclusion Criteria

Experiencing severe depression or current severe co-morbid diagnoses e.g. psychosis
Endorse 'yes, quite often' or 'sometimes' on question 10 of the Edinburgh Postnatal Depression Scale (EPDS; in the past 7 days, 'the thought of harming myself has occurred to me') at screening
Unable to complete informed consent and the questionnaires in English

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05628675). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.