N/A
N=159
Cardiorespiratory Fitness, Apolipoprotein E Genotype, and Cognitive Functions: A Prospective Study
Aging · Cognitive Change
Bottom Line
View on ClinicalTrials.gov: NCT05652140 ↗Enrolled (actual)
159
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Changes in Inhibitory Performance: Stroop Task — 1.66; -29.85; 21.49; -20.13 ms
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Data collections (Other)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- National Taiwan Normal University
- Primary completion
- Apr 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Changes in Inhibitory Performance: Stroop Task |
1.66; -29.85; 21.49; -20.13 | — |
| PRIMARY Changes in Neuroelectrical Activities |
-1.80; 2.81; -1.20; 0.57 | — |
| SECONDARY Number of Participants for Whom ApoE Genotype Was Determined |
22; 21; 57; 59 | — |
| SECONDARY Physical Fitness Measurements: Changes in Aerobic Fitness |
-4.03; 1.52; -4.76; 3.28 | — |
Summary
The current research project aims to investigate the interaction of cardiorespiratory fitness (CRF) and the ApoE genotype with neurocognitive functions.
Eligibility Criteria
Inclusion Criteria
- right handed
- no history of cardiorespiratory disease
- normal or corrected-to-normal vision based on the 20/20 standard
- no risk of performing physical activities, as measured by the Physical Activity Readiness Questionnaire
Exclusion Criteria
- the scores of Mini-Mental Status Examination (MMSE) < 25 and cognitively intact upon study entry
- history of psychiatric or neurological diseases
- color-blindness
Data sourced from ClinicalTrials.gov (NCT05652140). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.