N/A
Completed N=105
Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery
Older Adults · Anxiety · Depression · Major Surgical Resection of a Thoracic Malignancy
Source: ClinicalTrials.gov NCT05685511 ↗
Enrolled (actual)
105
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcomePrimary: PHQ-ADS — 18.35; 16.67; 17.51; 10.95 points
Summary
Using a Hybrid Type 1 Effectiveness-Implementation randomized control trial (RCT) design, the investigators will test the effectiveness of a bundled behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing oncologic surgery (compared with usual care), while examining implementation outcomes.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY PHQ-ADS |
18.35; 16.67; 17.51; 10.95; 12.52; 11.74 | — |
Eligibility Criteria
Inclusion Criteria
Pre-screening:
To be considered for participation, patients will be screened using PHQ-4 questionnaire. Scores >3 will indicate positive pre-screen (i.e. can be considered for participation and formal screening). Scores 10
- Acutely suicidal
- Considered ineligible per the discretion of the oncologic surgeon or study PI
- Previous participation in this study or another CPMH study of the intervention bundle or its feasibility.
Data sourced from ClinicalTrials.gov (NCT05685511). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.