N/A
Completed N=116
Perioperative Mental Health in Orthopedic Surgery
Source: ClinicalTrials.gov NCT05697835 ↗Enrolled (actual)
116
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcomePrimary: PHQ-ADS (Patient Health Questionnaire Anxiety and Depression Scale) — 16.84; 19.35; 11.26; 13.09 Points
Summary
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery (compared with usual care), while examining implementation outcomes.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY PHQ-ADS (Patient Health Questionnaire Anxiety and Depression Scale) |
16.84; 19.35; 11.26; 13.09; 9.08; 10.48 | — |
Eligibility Criteria
Inclusion criteria
- Adults ≥ 60 years
- Scheduled primary hip or primary knee arthroplasty procedure
- PHQ-ADS ≥ 10, indicating clinically significant depression or anxiety symptoms
Exclusion criteria
- Barrier to communication (Unable to read, speak, and understand English)
- Severe cognitive impairment screened by the SBT (Short Blessed Test) >10
- Acutely suicidal
- Previous participation in this study or another CPMH study of the intervention bundle or its feasibility.
Data sourced from ClinicalTrials.gov (NCT05697835). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.