N/A
N=51
Planning a Multi-Level Intervention to Reduce Substance Use Stigma in HIV Prevention and Care
Social Stigma · Substance Use Disorders · HIV Infections · Physician-Patient Relations
Bottom Line
View on ClinicalTrials.gov: NCT05925374 ↗Enrolled (actual)
51
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Provider-based Stigma (Social Distance Scale (SDS) Measure) — 9.09; 11.89 score on a scale — p=<0.001
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Substance use stigma training (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Wayne State University
- Primary completion
- May 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Provider-based Stigma (Social Distance Scale (SDS) Measure) |
9.09; 11.89 | <0.001 sig |
| PRIMARY Provider-based Stigma (Medical Condition Regard Scale (MCRS) Measure) |
22.70; 25.03 | 0.007 sig |
| PRIMARY Provider-based Stigma (Planned Behavior Measure Assessing Intention to Help Patients Who Use Drugs) |
3.19; 3.57 | 0.136 |
| PRIMARY Number of Participants Who Completed Focus Groups on Training Feasibility |
5 | — |
| SECONDARY Number of Participants Who Completed Qualitative Interviews on Policy Feasibility |
21 | — |
Summary
This is a community-engaged research project that aims to identify and pilot test interventions that may reduce substance use stigma among professionals at primary care sites serving patients who might be exposed to HIV or are living with HIV. Our goal is to develop a multi-level substance use stigma intervention that leverages 1) education and 2) organizational policy to address structural drivers of stigma and the stigmatizing professional attitudes and behaviors that affect patients. Hypothesis: the results of the trial pilot research and are expected to provide scientific evidence demonstrating feasible and potentially effective substance use stigma reduction interventions that go beyond simple individual-level professional training. We plan to build on the data from this pilot trial study to then further test the multi-level intervention in another larger trial study with primary care organizations to determine whether the intervention addresses multiple complex drivers of substance use stigma that influence HIV prevention and care outcomes among people who use drugs.
Eligibility Criteria
Inclusion Criteria
- Employed at a federally qualified health center (FQHC) or other primary care site
- For training and focus group participants (primary outcomes), volunteer is involved in direct interaction with patients
- For interview and trial feasibility survey participants (secondary outcomes), volunteer is a decision-maker at the FQHC and/or directly interacts with patients
Exclusion Criteria
- Not formally employed at a primary care facility (e.g., volunteer position at the site)
Data sourced from ClinicalTrials.gov (NCT05925374). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.