N/A
Completed N=6
ABSORB (Amount of Blueberries So Older Adults Reap Benefits)
Source: ClinicalTrials.gov NCT05937165 ↗Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcomePrimary: Urinary Flavonoid Biomarkers — 398863; 1045795 Unitless
Summary
This randomized, cross-over, pilot study aims to compare preliminary impact of a standard dose of blueberry powder (24 g) vs a higher dose (48 g) on the bioavailability of flavonoids and inflammatory biomarkers in older adults with minor levels of depressive symptoms.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Urinary Flavonoid Biomarkers |
398863; 1045795 | — |
| PRIMARY Inflammatory Biomarker C-reactive Protein |
-100; -635 | — |
| SECONDARY Inflammatory Biomarker Tumor Necrosis Factor Alpha |
-0.03; 0.06 | — |
| SECONDARY Inflammatory Biomarker Interleukin 6 |
0.28; -1.3 | — |
| SECONDARY Inflammatory Biomarker Interferon Gamma |
— | — |
Eligibility Criteria
Inclusion Criteria
- Men and women aged 65 years and older
- Minor levels of depressive symptoms (center for epidemiological studies depression scale, ≥4 and 3 cups/day)
- Recent and consistent use of antibiotics
- Currently taking or advised during the intervention to take anti-depressants
- Current homicidal or suicidal ideation (assessed via the P4 Suicidality Screener
- All deviations must be approved by the study sponsor
Data sourced from ClinicalTrials.gov (NCT05937165). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.