N/A
Completed N=200
Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)
Dementia · Depression · Behavior
Source: ClinicalTrials.gov NCT05980299 ↗
Enrolled (actual)
200
Serious AEs
21.5%
Results posted
Nov 2025
Primary outcomePrimary: Change in Physical Behavioral Symptoms Directed Toward Others — 4; 13; 1 Participants
Summary
The goal of this clinical trial is to test the feasibility of the Individualized Positive Psychosocial Interaction (IPPI) with 108 nursing home residents living with dementia and distress or depressive symptoms. The main questions it aims to answer are: •is it feasible to deliver the IPPI and track impact through data collected in the electronic medical records. Care partners will engage eligible residents in 2 brief preference-based IPPIs per week over the course of 6 months.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Physical Behavioral Symptoms Directed Toward Others |
4; 13; 1 | — |
| PRIMARY Change in Verbal Behavior Symptoms Directed Towards Others |
5; 12; 3 | — |
| PRIMARY Change in Other Behavioral Symptoms Not Directed Towards Others |
0; 18; 0 | — |
| PRIMARY Change in Rejection of Care |
5; 8; 0 | — |
| PRIMARY Change in Wandering |
3; 8; 1 | — |
| PRIMARY Change in Little Interest or Pleasure in Doing Things |
3; 15; 0 | — |
| PRIMARY Change in Feeling Down, Depressed or Hopeless |
2; 20; 1 | — |
Eligibility Criteria
Inclusion Criteria
Eligibility for Individualized Positive Psychosocial Interaction (IPPI)
- Be a long-term resident in a nursing home
- Have a score of 0-12 on the Brief Inventory for Mental Status (BIMS)
- Either (could be both) on their most recent Minimum Data Set (MDS) 3.0 assessment A score of 1 or higher on any of the 5 behavior items from MDS Section E (i.e., physical, verbal, other behavior, rejection of care, wandering) A score of 1 or higher on one of 5 MDS section D items (i.e., anhedonia, sad mood, poor self-esteem, poor appetite, restlessness)
Exclusion Criteria: Nursing home residents who are expected to live in the community for less than 6 months.
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Data sourced from ClinicalTrials.gov (NCT05980299). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.