N/A
N=78
AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport
Oxygenation · Manual Ventilation · Mechanical Ventilation · Point of Care Ultrasound · Cardiac Function Disturbance Postoperative
Bottom Line
View on ClinicalTrials.gov: NCT06006208 ↗Enrolled (actual)
78
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcome: Primary: The % Change in Mean Artery Blood Pressure — -3.73; 13 % change in mean artery pressure
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Hamilton C1 ventilator during transport to the ICU (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Thomas Jefferson University
- Primary completion
- Oct 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The % Change in Mean Artery Blood Pressure |
-3.73; 13 | — |
| SECONDARY The % Changes in PaO2/FiO2 (P/F Ratio) |
6.76; -12.2 | 0.275 |
| SECONDARY The % Change in PaCO2 |
3.42; 3.06 | 0.891 |
| SECONDARY The Visual Scale in Changes in Left Ventricular Function |
0; 0 | — |
| SECONDARY The Visual Scale in Changes in Right Ventricular Function |
0; 0 | — |
Summary
This is a clinical trial to compare the oxygenation and ventilation performance between manual ventilation and mechanical ventilation when transporting cardiac patients to the ICU.
Eligibility Criteria
Inclusion Criteria
- Over 18 years old (any gender or race)
- Cardiac surgery
- Require postoperative mechanical ventilation and care in the ICU.
Exclusion Criteria
- Patients' refusal
- Extubation in OR
- On mechanical circulatory support
- Requirement for postoperative therapy with inhaled pulmonary vasodilators (epoprostenol (FLOLAN), inhaled nitric oxide, etc.)
- Severe RV dysfunction with preoperative echocardiography
- Contraindication to TEE and pulmonary artery catheter.
Data sourced from ClinicalTrials.gov (NCT06006208). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.