N/A
Completed N=36
Stroke and CPAP Outcome Study 3
Stroke · Intra Cerebral Hemorrhage · Obstructive Sleep Apnea · Adherence, Treatment
Source: ClinicalTrials.gov NCT06029959 ↗
Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcomePrimary: CPAP Adherence — 3.1 nightly hours of CPAP use
Summary
A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors. There is also evidence that OSA predicts worse outcome after stroke. The question being addressed in the Stroke and CPAP Outcome Study 3 (SCOUTS3) is how to improve use of continuous positive airway pressure (CPAP) therapy to treat OSA when started during intensive stroke rehabilitation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY CPAP Adherence |
3.1 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18 years or older
- Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days
- Person providing consent (patient or legally authorized representative) able to be consented in English or Spanish
Exclusion Criteria
- Unable to obtain informed consent from participant or surrogate
- Incarcerated
- Known pregnancy
- Current mechanical ventilation, tracheostomy or supplemental oxygen use > 4L/min
- Current use of positive airway pressure or use within 14 days prior to stroke
- History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use
- Stroke related to tumors, vascular malformations or subarachnoid hemorrhage
- Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA)
- Anticipated inpatient rehabilitation length of stay < 3 nights
Data sourced from ClinicalTrials.gov (NCT06029959). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.