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N/A N=165

Hypoxemia in the First 24 Hours After Trauma - an Observational Study

Trauma · Trauma Injury · Hypoxemia · Hypoxia · Oxygen Deficiency

Enrolled (actual)
165
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcome: Primary: Occurrence of Hypoxemia — 5.1; 5.1 IR of episodes pr. 100 participant-hours — p=0.95

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Pulse oximeter (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Rigshospitalet, Denmark
Primary completion
Aug 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Occurrence of Hypoxemia
5.1; 5.1 0.95
SECONDARY
Location of Hypoxemia (Specific Departments)
6.7; 4.5; 6.4; 8.5; 6.6; 0 1
SECONDARY
Prolonged Hypoxemic Episodes
0.9; 1.0 0.83
SECONDARY
Cumulated Time of Hypoxemia
5.5; 3.0 0.05

Summary

The goal of this observational study is to investigate the occurrence of hypoxemia (an abnormally low concentration of oxygen in the blood) in trauma patients within the first 24 hours of hospital admission following arrival to a trauma center. The main questions the study aims to answer are: * Do trauma patients experience hypoxemia during the initial 24 hours of hospital admission following trauma? * What is the daily distribution of potential hypoxemic episodes? The investigators expect that hypoxemic episodes will be more frequent during the night (20.00-07.59) than during the day (08.00-19.59) An additional pulse oximeter will be attached to the participants, which measures oxygen saturation in the blood during the first 24 hours of hospital admission after trauma.

Eligibility Criteria

Inclusion Criteria

  • Patients aged ≥18 years
  • Blunt or penetrating mechanism of trauma
  • Trauma team activation
  • Admission to a ward/ICU from trauma centre

Exclusion Criteria

  • Patients with a suspicion of carbon monoxide intoxication
  • No applicable finger or toe for sensor attachment
  • Trauma team activation was cancelled
  • No available pulse oximeter at admission
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06256692). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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